Key features of depression and its management in general practice.

 
"..I'm not like I was before.."

Which of the following statements are true of choice of antidepressants for Ellen?
1. Patients with cardiac disease should be treated with tricyclic antidepressants which have less cardiotoxicity than selective serotonin reuptake inhibitors.
2. Patients with acute angle glaucoma should be commenced on selective serotonin reuptake inhibitors which have minimal anticholinergic adverse effects.
3. In clinical practice no individual differences in response are seen within drug classes.
4. Combinations of antidepressants are more effective than monotherapy.
5. Tricyclic antidepressants are safer in overdose than selective serotonin reuptake inhibitors.
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