MEASLES EPIDEMICS IN TURKEY AND DEVELOPING COUNTRIES: REVIEW OF THE LITERATURE

During 2001-2002, two outbreaks of measles occurred in Venezuelan states near the border with northern Colombia (measles vaccination coverage in these states was lower compared Venezuela General, e.g., Falcón, 44%; Zulia, 34% vs. 84%). The outbreak spread to Colombia in January, 2001 and ended after implementation of a statewide vaccination campaign for children aged 1-14 years. During these outbreaks, measles surveillance has been heightened by using active case searches in both countries, with 2198 suspected cases detected (5.4 per 100000 population) in Colombia and 6380 (26.5) in Venezuela. The age groups most affected were children aged <5 years, children aged 5-9 years, and persons aged 20-29 years. Finally, editors concluded that low vaccination coverage in Venezuela and deficiencies in surveillance contributed to the outbreak (31).

As a conclusion, measures to control measles outbreaks must include 1) partnerships with local municipalities and international health organizations (e.g., WHO, UNICEF), 2) rapid identification and vaccination of groups at high risk (e.g., health-care workers, migrants, and tourist industry personnel), 3) an additional dose at 6-9 months for Infants at high risk (HIV-infected, vitamin A deficient, in closed communities such as refugee camps, or in the face of an outbreak), 4) house-to-house monitoring of vaccination coverage, 5) heightened surveillance in all regions of the endemic countries.

References
1.
World Health Organization. Global measles mortality reduction and regional elimination, 2000-2001. Weekly epidemiological record 2002; 77:49-56 (http://www.who.int/wer).
2. Schlereth B, Rose JK, Buonocore L, ter Meulen V, Niewiesk S. Successful Vaccine-Induced Seroconversion by Single-Dose Immunization in the Presence of Measles Virus-Specific Maternal Antibodies. Journal of Virology 2000; 74(10): 4652-4657.
3. Chen RT, Markowitz LE, Albrecht P, Stewart JA, Mofenson LM, Preblud SR, Orenstein WA. Measles antibody: reevaluation of protective titers. J Infect Dis 1990; 162: 1036-1042.
4. Sato, H, Albrecht P, Reynolds DW, Stagno S, Ennis FA. Transfer of measles, mumps and rubella antibodies from mother to infant. Its effect on measles, mumps and rubella immunization. Am J Dis Child 1979; 133: 1240-1243 [Medline].
5. Schoub BD, Johnson S, McAnerney JM, Wagstaff LA, Matsie W, Reinach SG, et al. Measles, mumps and rubella immunisation at nine months in a developing country. Ped Infect Dis J 1990; 9:263-267 [Medline].