Abstract
Introduction:
Comprehensive analysis was
conducted on available guidelines
to identify gaps in the available
evidence for effective approaches
to lipid management. The four
guidelines included in the
review are NICE, ESC, CCS
and AHA/ACC/MS.
Method:
Multiple databases were
explored to locate relevant
guidelines published within
the past decade, until June
17, 2023. A qualitative comparison
was made regarding recommendations
on testing frequency, lipid-lowering
therapies, and target cholesterol
levels.
Results:
All the guidelines unanimously
advocated for statins as the
primary therapy for reducing
lipid levels. Noteworthy disparities
were observed in the recommended
cholesterol targets across
the various guidelines. Each
guideline provided a specific
target for the level of low-density
lipoprotein cholesterol (LDL-C).
For long-term patient monitoring,
many of the guidelines (n=2)
recommended annual reviews,
although some variations were
noted, suggesting intervals
ranging from 3 weeks to 12
months.
Conclusion: All the guidelines
have the same scope, despite
a few disparities, future
research should focus on resolving
these differences and on optimizing
the preventive measures for
lipid management.
Keywords:
lipid management, guidelines,
review
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