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WFM / MEJFM July 2024

Histopathological interpretation of endometrium in abnormal uterine bleeding

Nansi Dari Alfayez 1, Ala aldin ahmed hussain hindawi 2, Gharam Abu-Assaf 3 ,Ahmad zuhier momani 3, Omayah mohammed awad alquran 3,
Hind mohamad al qatamin 4

(1) MD Consultant gynecologist in Royal Medical Services
(2) MD Senior specialist gynecologist in Royal Medical Services
(3) MD, specialist gynecologist in Royal Medical Services
(4) MD, specialist histopathologist in Royal Medical Services

Corresponding author:
Nansi Dari Alfayez MD
Consultant gynecologist in Royal Medical Services
Jordan
Email: nansialfayez80@hotmail.com

Received: May 2024. Accepted: June 2024; Published: July 1, 2024.Citation: Nansi Dari Alfayez et al. Histopathological interpretation of endometrium in abnormal uterine bleeding. World Family Medicine. July 2024; 22(6): 6-10. DOI: 10.5742/MEWFM.2024.95257670


Abstract


Background:
Abnormal uterine bleeding is an unusual and irregular uterine bleeding. It is considered one of the gynecological complications which significantly affects patients, patients family, social activities and quality of life.

Objective: to evaluate and interpret the endometrial histological findings among women with uterine bleeding.

Methods: This study was conducted in the Department of Obstetrics and Gynaecology at Prince Hashime /Az zarqa in Royal Medical Services RMS during the period 2018 to 2020. Purposive sampling technique was used to select two hundred patients diagnosed with abnormal uterine bleeding who underwent endometrial sampling after dilatation and curettage. A cohort study was used to evaluate and interpret the endometrial histological findings among women with abnormal uterine bleeding.

Results: A maximum number of cases with abnormal uterine bleeding was found in reproductive fertile age group 20 to 40 years (60.42 %) in women with parity 2-5 (90.25%). Menorrhagia was the major symptom in 76 cases and represented 35.94%, and for the secretory endometrium the highest percentage was (34.42%) of all the cases. Menorrhagia was the commonest mode of the entire age group, with 50% in the group <20 years. Metrorrhagia and metropathia haemorrhagica were higher in the reproductive age group rather than the age group >40 years.

Conclusions: The greatest percentage of abnormal uterine bleeding was found in the group of 20-40 years in multiparous women and Menorrhagia was the commonest in all age groups. The majority of the patients with secretory and proliferative endometrium had normal uterus size and normal form of endometrium. 50 % of all patients had cheesy endometrium and enlarged uterus in patients with atypical hyperplasia.

Keywords: Endometrium, Hyperplasia, abnormal uterine bleeding, Metrorrhagia,
Perimenopausal, Nulliparous





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