Zainab is a 6-year old girl who was referred by the PHCC Physician for evaluation of her persistent low hemoglobin levels. Her family members were healthy. On examination, she was adequately nourished, but had mild pallor and splenomegaly of 5 cm below costal margin. Lymphadenopathy, - no  bone pains or  petechiae were detected.

Investigations:
 

haemoglobin

7.5 mg/dl 

reticulocytes

300 x 109/l 

haemoglobin electrophoresis

A 97% A2 3% 

peripheral smear

Examination small, dense, circular red blood cells and red blood cells with polychromasia

direct antiglobin test

Negative