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             1. 
              Two depressive episodes within 5 years is an indication for long-term 
              medications.  
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              2. Long-term treatment should be continued for at least 3 years. 
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             3. 
              Antidepressants of all classes are effective in the long-term prevention 
              of depression.  
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             4. 
              Lithium is effective in the long-term prevention of depression. 
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             5. 
              A reduced maintenance dose of 30 to 50 percent below the acute dosage 
              is as effective as a full acute dose in the long-term prevention 
              of depression.  
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