Key features of depression and its management in general practice.

 
"..I'm not like I was before.."

Which of the following statements are true for Ellen?
1. Patients who are started on antidepressants should be seen weekly for the first six weeks.
2. Selective serotonin reuptake inhibitors usually start to work within the first week of treatment.
3. Full recovery may take 6 weeks or longer when using selective serotonin reuptake inhibitors.
4. A 25% or greater reduction in baseline symptom severity is an adequate therapeutic response.
5. The antidepressants should be continued for at least six months.
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1. Patients who are started on antidepressants should be seen weekly for the first six weeks.

Author's answer: True

Patients with major depression who are started on antidepressants should be seen weekly and those with less severe illness every 10 to 14 days during the initial 6 to 8 weeks of pharmacotherapy. This schedule optimises patient compliance, facilitates dosage adjustment, and permits more careful monitoring.

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