 Key features of depression and its management in general practice. |
| "..I'd like to return to work.." |
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Which
of the following statements are true of the management of depression |
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1. The elderly tolerate tricyclic antidepressants better than SSRIs. |
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2. Adverse effects of SSRIs are more problematic in older patients than younger patients. |
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3. SSRIs interact with beta-blockers. |
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4. Hormone replacement therapy is useful in the management of depression in the elderly. |
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5. Electroconvulsive therapy is useful in the management of psychotic depression in the elderly. |
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1. The elderly tolerate tricyclic antidepressants better than SSRIs.
Author's answer: False.
As in younger adults, the elderly tend to tolerate the SSRIs better than TCAs. This finding is based on fewer anticholinergic effects, little or no adverse effects on cognition in recommended doses, and minimal cardiovascular effects.
The TCAs vary with respect to side effect profile, but certain adverse effects such as orthostatic hypotension, sedation, and cardiac toxic effects can be particularly problematic in older persons.