This issue of the journal has a good number of paper discussing various issues of importance to health. Hadi et al., did an extensive review on Physical and psychological impacts of cancer on children and adolescents and strategies to improve it. The authors stressed that childhood cancer is a major cause of morbidity and mortality. Globally, cancer is one of the most sever health illness among children and adolescents. every year approximately 151,435 cases with cancer are diagnosed that lead to physical and psychological impacts on children and adolescent (Cancer Statistics Center, 2020 & Schüz, J.; Roman, E, 2021). Furthermore, previous data from the World Health Organization showed approximately 400,000 children and adolescents aged 0-19 are diagnosed with cancer annually (WHO, 2021). A young population with longer life expectancies and a recognized rising cancer burden both locally and globally pose challenges to providing the finest healthcare. The authors concluded that their literature review highlighted precise evaluation of physical and psychological impacts of cancer among children and their parents that necessary to guarantee excellent care and efficient therapy and to find best ways to decrease these impacts.

Alenazi, et al., reviewed the use of artificial intelligence in nursing education. This study uses a quantitative research design and regression analysis to examine the impact of artificial intelligence (AI) integration on nursing students' attitudes and academic performance. A sample of 300 nursing students was surveyed to identify key factors influencing their acceptance and use of AI technology in their education. Results revealed that technological proficiency and positive attitudes toward AI significantly predicted improved academic performance. These findings have significant practical implications for curriculum development in nursing education, emphasizing the importance of integrating AI and enhancing students' technological skills.

Asim, et al ., presented a case of cardiac amyloidosis. They pointed that Amyloidosis is a multisystem disorder. Cardiac involvement causes restrictive cardiomyopathy. A 65yrs old gentleman presented with worsening shortness of breath. Investigations including echo and cardiac MRI showed cardiomyopathy consistent with amyloidosis. Cardiac involvement is related with poor prognosis and increased mortality.

Iqbal et al., discussed the benefits of fasting. They stressed that there has been increased popularity of fasting as a lifestyle choice and a way of losing weight. Overall, fasting results in significant health benefits. Fasting during Ramadan (i.e. religious fasting) leads to additional benefits. In their second paper they discussed Reaction to aluminium in vaccines. They stressed that Some children can develop nodules at the site of their immunisations. These are granulomas due to a reaction with aluminium which is present in some vaccines. The nodules are benign and further investigations are not needed. The nodules can cause intense itching and treatment is aimed at treating this until the nodules resolve on their own.

Nehal et al., reviewed Trigeminal Neuralgia. It is a facial pain disorder characterised by recurrent paroxysmal pain emerging from neurovascular compression of the trigeminal nerve or its branches. Epidemiological studies show TN to be a rare disease with increased prevalence in women and older populations. The pathophysiology is largely unknown and is multifactorial in nature, that involves genetic, neuroanatomical, physiological, and morphological risk factors. It is caused by hyperexcitable neuronal states that alter neuronal plasticity. TN is classified as classical, secondary, and idiopathic, primarily, and based on its differential diagnosis it can be differentiated from other similar neuropathic pain. Brain and facial imaging are the most common diagnoses to determine TN. Treatment of TN is aimed at reducing the painful episodes in patients, both by frequency and severity. It is provided based on physiological features, patient age and sex, subtype of TN, comorbidities, disease severity, and MRI imaging. It initiates with first-line pharmacotherapy which includes common anti-seizure medications, followed by second-line drugs in monotherapy or in combination till the symptoms subside. In case of persistent symptoms, surgical procedures like microvascular decompression, or percutaneous neuroablation can be considered. For future advancement, understanding the pathophysiology of TN is crucial, as well as such knowledge may aid in developing more effective and more tolerable therapies. Designing better epidemiological studies in TN and advancement in diagnostics and functional studies is warranted which provide critical insights for the management of TN.

Ayoub et al., discussed the Crucial Role of Pneumococcal Vaccination in Hajj Pilgrimage: Advocating for Compulsory Policy Changes. The annual Hajj pilgrimage to Mecca brings together millions of individuals from diverse geographic regions, presenting significant public health challenges, particularly concerning the transmission of infectious diseases. This article highlights the critical importance of pneumococcal vaccination as a preventive measure during Hajj. Given the heightened risk of respiratory infections in such a densely populated and international gathering, the authors advocate for making pneumococcal vaccination compulsory for all pilgrims. The article discusses the public health benefits of widespread vaccination, including the reduction in cases of pneumonia, meningitis, and sepsis caused by Streptococcus pneumoniae. It also examines potential barriers to implementing compulsory vaccination policies, such as logistical challenges, vaccine hesitancy, and the need for culturally sensitive approaches. The authors emphasize the necessity of collaboration among health authorities, religious leaders, and pilgrims to ensure successful policy implementation and enhance health outcomes during the pilgrimage.

Hussain, et al., report a case report on Early Diagnosis and Management of Acute Pericarditis in a patient with G6PD deficiency. They pointed that Pericarditis, caused by infections, autoimmunity, or trauma, often causes sudden chest pain and may result in complications like pericardial effusion and cardiac tamponade, affecting patient outcomes. A 30-year-old male with G6PD deficiency and asthma presented with acute pleuritic chest pain post-upper respiratory tract infection. The evaluation revealed muffled heart sounds, global ST elevation on ECG, elevated CRP (119mg/L) and troponin T (445ng/L). An echocardiogram showed preserved left ventricular systolic function and an MRI confirmed acute myopericarditis. Colchicine therapy was initiated but discontinued after six weeks due to liver function test abnormalities, following which the patient made a full recovery. This case emphasizes viral-triggered pericarditis's presentation, stressing early diagnosis and management. Despite colchicine's temporary liver impact, prompt treatment resulted in full recovery, highlighting early intervention's effectiveness in avoiding complications. The authors concluded that this case illustrates the critical role of prompt diagnosis and careful management in achieving favorable patient outcomes.