PREVENTION OF POST PARTUM HAEMORRHAGE BY RECTAL MISOPROSTOL. A RANDOMISED CONTROLLED TRIAL.

Table 3 Outcome measures among the two groups

Variable
Misoprostol group
n= 198
Oxytol in group n= 204
p
Postpartum Haemorrhage
(= 500)*
14(7%)
12 (6%)
0.628
Drop in Hematocrit Level (%)#
4.6%+/- 4.2
4.5%+/-4.1
0.675
Drop in Haemoglobin level (%)#
1.4+/-1.3
1.3+/-1.2
0.674

Data are presented as mean + SD, unless otherwise indicated
*Not statistically significant deference among groups (p > 0.05) X2 (chi- square test)
#Not statistically significant deference among groups (p > 0.05) t-test (student test)

A 10% drop in hematicrit was observed from admission to day one postpartum occurred in 4.6% of the study subjects and in of 4.5% of the control subjects (p=0.674).

There were no significant differences in the number of women who required additional oxytocin to control bleeding after delivery. The length of the third stage of labour was similar in both groups 10 and 8 minutes respectively.

Regarding the side effects, shivering was observed with equal frequencies in both groups ~10%. Other side effects as nausea, vomiting and diarrhoea were the same in both groups. Similar neonatal outcomes (birth weight and Apgar score) were observed in both groups.