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November2022 -
Volume 20, Issue 11


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From the Editor

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Awareness and attitude toward antidepressants in the population of Riyadh, Saudi Arabia
[Abstract]
[pdf]
Yasir Ibrahim Alsenaidi, Omar Dawas AlDawas, Abdullah Ahmad AlFihaid, Mohammed Sultan AlZimami, Rayan Faleh AlQahtani, Khalid A. Bin Abdulrahman
DOI: 10.5742/MEWFM.2022.95251360

Predictive factors of postoperative paralytic ileus following abdominal surgery: a clinical study
[Abstract]
[pdf]
Tamer M. Abdelrahman, Ahmed K. Alharthi, Salem S. Alamri, Amer M. Alnefaie, Baraa A. Omar, Mohammed A. Alzahrani
DOI: 10.5742/MEWFM.2022.95251361


Burden, clinical aspects and correlates of dyspepsia among the population in Jeddah, Saudi Arabia
[Abstract]
[pdf]
Fathi El-Gamal, Lujain Baajajah, Ghufran Katib, Shaima aljohani, Ghada aljuhani, Huda Zahra
DOI: 10.5742/MEWFM.2022.95251362

Medical students' understanding and interpreting abilities for Complete Blood Counts (CBC) in clinical practice
[Abstract]
[pdf]
Tahir Jameel, Mukhtiar Baig, Mohammed Ibrahim Mohammed Albejad,
Taha Mohammed Abdullah Aljifri, Bander Abdualziz Taher Almaghrabi,
Raneem Youseef Qashqaui
DOI: 10.5742/MEWFM.2022.95251363

Post-catheterization complications in diabetic patients with myocardial infarction
[Abstract]
[pdf]
Ali Mohammed Alamri, Mohammed Dafer Alahmari,
Amar Abdullah A. Al Qahtani, Amjad Abdulrahman H. Al Qahtani,
Sabah Mubarak H. Alshahrani, Lujain Saleh A. Alamri, Walaa Muteb D Alahmari,
Amnah Saad H Alharthi, Manar Abdullah S Alqahtani
DOI: 10.5742/MEWFM.2022.95251374

Assessment of Quality of Life among Elderly Patients Attending Primary Healthcare Centers in Aseer Region, Saudi Arabia
[Abstract]
[pdf]
Osama Mohammed Alqahtani, Awad Saeed Alsamghan, Safar Abadi Alsaleem, Alaa Ali Saeed Alyahya, Faizah Salem Alrazhi, Asma Sulaiman Alshahrani,
Atheer Saeed M Alasmary, Asma Abdullah Saeed, Ranyah Ahmed Nasser Gwadi, Bushra Mohammed Alotayfi, Nadine Thabet Saeed Alshahrani
DOI: 10.5742/MEWFM.2022.95251375

Factors affecting patients' waiting time at the Radiology Department
[Abstract]
[pdf]
Waleed Abdullah Ali Omar, Reham Mohammed Al-Shahrani,
Mohammed Ahmed Almushafi, Hussein M. Boraie
DOI: 10.5742/MEWFM.2022.95251376

Elastography as predictor for thyroid nodule malignancy
[Abstract]
[pdf]
Reyad Alsuqair, Nermeen Omar, Sultanah Alshreef, Yazeed Alharthi,
Mohammad Algarni, Abdulaziz Aljuaid, Omar J. AlThaqufi
DOI: 10.5742/MEWFM.2022.95251378

Population and Community Studies

Knowledge, Attitude and Perceptions of the population towards Vitamin D in Jeddah, Saudi Arabia
[Abstract]
[pdf]
Fathi El-Gamal, Ahmed Daghmash, Amjad Yapah, Ahmed Buraymah,
Farah AL Tahawi, Fatima Khairurllah
DOI: 10.5742/MEWFM.2022.95251364

The Prevalence of Constipation and Its Associated Complications in Aseer Region by Using Wexner Scale
[Abstract]
[pdf]
Muneer Jan Bhat, Sultan Mohammed Abdullah Alkorbi,
Nejad Mubasher Mohammed Almaem, Abdullah Omar Musleh Alqarni,
Shadi Ahmad Abdullah Alamri, Lama Gasem Asiri, Khalid Ali Abdullah Alsaiary
DOI: 10.5742/MEWFM.2022.95251365

Association Between Blood Donation and Improved Sleep Quality Among Blood Donors in Aseer Region
[Abstract]
[pdf]
Mohammed Abdulrahman Alshibli, Zayed Mofareh Ahmed Asiri,
Ghanem Ahmed Mohammed Al Ghanem, Musaad Abdulrahman M Al Shibli,
Naif Mohammed Alotaibi, Saeed Abdullah Saeed Alasmari,
Abdullah Safar Saeed Al safar, Bader Saad S Alshahrani, Nada Hamzah Albarqi, Naif Sultan S Alqahtani, Abdulrhman Abdullah Ali Mansour DOI: 10.5742/MEWFM.2022.95251366

Parental awareness of pediatric foreign body aspiration in Taif city, Saudi Arabia
[Abstract]
[pdf]
Badr S. Alam, Mohammed Althomali, Amjad Jawhari, Khalid Faraj,
Abdulaziz Alghuraibi, Abdulrahman Alsubaie, Sattam Aljuaid
DOI: 10.5742/MEWFM.2022.95251367

Assessment of level of knowledge about cryptorchidism and its complications among paternity age population in the western region of Saudi-Arabia. Cross-sectional Questionnaire based study
[Abstract]
[pdf]
Faisal M. Alfadli, Abdulaziz S. Aljuaid, Muhanad A. Althbaiti,
Abdulrahman D. Alhamyani, Ahmed S. Alsoaimi, Khalid M. Alzahrani
DOI: 10.5742/MEWFM.2022.95251368

Knowledge, attitudes, and practices of self-ear cleaning among the general population in Riyadh, Saudi Arabia
[Abstract]
[pdf]
Khalid A. Bin Abdulrahman, Faisal A. Alhazani, Faisal T. Alayed,
Abdulrahman A. Alomar, Abdulmajeed H. AlSarrani, Abdulaziz M. Albalawi,
Firas O Alhussini
DOI: 10.5742/MEWFM.2022.95251370

Assessment of patients' knowledge and attitudes towards self-insulin administration and skin manifestations in the regions of Aseer
[Abstract]
[pdf]
Rawan Shawabkeh, Muteb Aldajam, Halimah Alshehri, Mohammed Muqri, Mohammed Mukharrib, Mahdi Alzamanan, Mona Alhamad, Sukayna Alhamad, Haya Alnumayr, Muidh Aldajam, Hisham Alqahtani
DOI: 10.5742/MEWFM.2022.95251387

Regional Covid

The Knowledge and Attitude of Precautionary Measurements for COVID-19 Pandemic Among College Students: A Cross-Sectional Study in Jeddah City, Saudi Arabia
[Abstract]
[pdf]
Anas S. Alyazidi, Mahmoud A. Gaddoury, Hussain A. Alkhalifah,
Fahad A. Alotibi, Hani A. Turkstani, Abdulaziz T. Jambi, Waheeb S. Aggad DOI: 10.5742/MEWFM.2022.95251371

Education and Training

Experience of undergraduate medical students of Al-Imam Mohammad ibn Saud Islamic University (IMSIU) about the international summer elective program (ISEP)
[Abstract]
[pdf]
Khalid Bin Abdulrahman, Alswayed, Khalid E., Alomar, Naif A., Al Thaqfan, Naif A.
Abozaid, Hesham S
DOI: 10.5742/MEWFM.2022.95251373

Efficacy of Dienogest for Prevention of Endometriosis Recurrence: A Systematic Review and Meta-Analysis
[Abstract]
[pdf]
Hussain MA Assiri, Mashail AS Alomari, Atheer DM Alshehri, Asma SY Alahmari, Manal M Alasmari
DOI: 10.5742/MEWFM.2022.95251391

Empathy level among Saudi medical students using the Toronto empathy scale
[Abstract]
[pdf]
Khalid A. Bin Abdulrahman, Majed A. Alsharidah, Badr A. Alobaida,
Yazeed N. Alabbadi, Faisal I. Almohsen, Tamim A. Abahussain, Faisal S. Alahmari
DOI: 10.5742/MEWFM.2022.95251392

Reviews

Vascular dementia - A Narrative Review
[Abstract]
[pdf]
Nasir Alzbeidi, Hamed Alsinawi, Hem Phaterphaker
DOI: 10.5742/MEWFM.2022.95251395

Role of MR in Evaluating Multiple Sclerosis
[Abstract]
[pdf]
Rahaf Saad Mohammed Al Jallal, Marwah Saad Mohammed Al Jallal
DOI: 10.5742/MEWFM.2022.95251397

Retrospective study

Middle East Quality Improvement Program
(MEQUIP QI&CPD)


Chief Editor -
Abdulrazak Abyad MD, MPH, MBA, AGSF, AFCHSE

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Publisher -
Lesley Pocock
medi+WORLD International
AUSTRALIA
Email
: lesleypocock@mediworld.com.au
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The contents of this journal are copyright. Apart from any fair dealing for purposes of private study, research, criticism or review, as permitted under the Australian Copyright Act, no part of this program may be reproduced without the permission of the publisher.

   
December 2022-January 23 - Volume 20, Issue 13

A case report of relapse of minimal change disease after the first dose of Pfizer-BioNTech Covid-19 vaccine in King Abdul-Aziz Specialist Hospital, Taif, Saudi Arabia

(1) Consultant, nephrology department, King Abdul-Aziz Specialist Hospital, Taif, Saudi Arabia
(2) Medical intern, King Abdul-Aziz Specialist Hospital, Taif, Saudi Arabia

Corresponding author:

Dr. Shatha K. Alhalbi
Taif city, Saudi Arabia
Tel.:0593245934
Email: shatha.nae@gmail.com

Received: November 2022 Accepted: December 2022; Published: December 15, 2022. Citation: Faisal K. Alhomayani, Shatha K. Alhalbi, Elaf M.. A case report of relapse of minimal change disease after the first dose of Pfizer-BioNTech Covid-19 vaccine in King Abdul-Aziz Specialist Hospital, Taif, Saudi Arabia. World Family Medicine. December 2022 - January 2023; 21(1): 145-151 DOI: 10.5742/MEWFM.2023.952515016

Abstract



Background: Documented cases of de novo glomerular disease or relapse of pre-existing glomerular disease was acquired shortly after administration of COVID-19 messenger RNA (mRNA) vaccinations.

Objectives: to present a case of a 64-year-old female who received the Pfizer-BioNTech COVID-19 vaccination as a first dose and then experienced a relapse of minimal change disease (MCD) presenting with nephrotic syndrome.

Case presentation: The presenting symptom was ankle swelling and frothy urine which started 9 days after the first dose of vaccine. Albumin level was 24 g/L, urine albumin/creatinine ratio was 668 mg/mmol, Creatinine had risen to 1.3 mg/dl, urine analysis showed 3+ protein. light microscopy showed 17 patent glomeruli, one of which was globally sclerosed. There was mild focal increase in mesangial matrix with occasional atrophic tubules with minor interstitial scarring affecting less than 5% of cortical area. There was moderate fibrointimal thickening. In electron microscopy, 100% of podocyte foot process were effaced with microvillation and marked cytoplasmic vacuolation. The findings were consistent with minimal change disease (MCD) with mild chronic renal parenchymal damage. The patient started furosemide 80 mg daily for 21 days after the onset of complaints. prednisolone 1 mg/kg was initiated 1 week and patient`s symptoms improved. The patient achieved a complete remission 4 weeks after initiation of prednisolone.
Conclusion: For the best management of MCD as a potential side effect following COVID-19 vaccination, more knowledge is required.

Keywords: case, relapse, MCD, Pfizer-BioNTech, Covid-19, Taif







 


 

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