Key features of depression
and its management in general practice. |
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"..I've
been possessed by the devil"
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| Which
of the following statements are true in relation to withdrawal of
Omar from his antidepressants? |
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1.
Carbamazepine is effective as long term prophylaxis. |
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2.
Sodium valproate is now used widely for maintenance treatment. |
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3.
Angiotensin converting enzyme inhibitors may cause lithium toxicity
in people taking the drug. |
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4.
Omar should have his thyroid function monitored every 6 to 12 months. |
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5.
Cessation of lithium should be gradual, over at least 1 to 2 months. |
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5.
Cessation of lithium should be gradual, over at least 1 to 2 months.
Author's
answer: True
Abrupt
cessation of lithium may lead to relapse of mania (or, less likely,
depression) in many bipolar patients within the next few months. Therefore,
if lithium is to be ceased, this should be undertaken slowly over at
least 1 to 2 months.
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