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October 2022 -
Volume 20, Issue 10


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From the Editor

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Publisher
Lesley Pocock
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Editorial
Abdulrazak Abyad

Letter to Editor

International Family Medicine Conference & Exhibition - IFM 2022
Dubai, UAE
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Original Contribution

Evaluation of physical performance and quality of life among patients with previous kidney transplantation: A Cross-sectional study
Shami, Mohammed Adel M, Abdulrahman Mohammed Ali, Saud Mohammed Saud Aleisa, Meshari Ghali Alnefaie
[Abstract]
[pdf]
DOI: 10.5742/MEWFM.2022.9525174

Investigating the awareness of breast cancer among female pharmacy students in the Makkah region, Saudi Arabia
Jumana Sako, Ghdi Almsaoudi, Rasha AL-Malki, Raghidah Alilyyani,
Rawan Almatrafi, Raghad Almatrafi, Nouf Alwafi, Shuruq Alamer,
Rehab Almehmadi, Reem Alotaibi, Safaa Alsanosi, Alaa Falemban,
Deena Bukhary, Yosra Al-Hindi
[Abstract]
[pdf]
DOI: 10.5742/MEWFM.2022.9525175

Assessing Medical Student Basic Otolaryngology Knowledge:
A questionnaire-based Study
Yahya A. Fageeh, Mohammed A. Basurrah, Abdulaziz S. Aljuaid, Abdulmohsen H. Alghamdi, Rayan D. Alamri, Hamoud A. Alobaylan, Mujahid A. Alzahrani
[Abstract]
[pdf]
DOI: 10.5742/MEWFM.2022.952596

Outcome of Antenatal Renal Pelvic Dilatation - Review of Cases from a Tertiary Care Center, in the Armed Forces Hospital, Southern Region, Saudi Arabia
Khalil Mahmoud, Abdullah Mohammed, Basim Qusayri, Bayan Hanif, Mohamed Ayed, Ahmad M. Elabed, Ahmed Kandeel Elhaddad
[Abstract]
[pdf]
DOI: 10.5742/MEWFM.2022.9525187

Regional Covid

COVID-19 Effect on Dietary Supplements' Consumption, Prophetic Medicine Practices and Herbs Use in Saudi Arabia
Elham Abbas Aljaaly, Reem Alhijri, Lujain Al Nasser
[Abstract]
[pdf]
DOI: 10.5742/MEWFM.2022.952597

Self-Reported Adverse Events of COVID-19 Vaccines on Menstrual Cycles
Afaf Farouq Alzahrani, Nada Abdulfattah Abdulaal
[Abstract]
[pdf]
DOI: 10.5742/MEWFM.2022.9525188

Willingness and attitudes of parents of children under the age of 12 about the COVID- 19 vaccine in Taif city
Ayman A. Atalla, Jamal Faydh, Saad Althuwaybi, Ethar Alharthi, Amani Alrumaym
[Abstract]
[pdf]
DOI: 10.5742/MEWFM.2022.9525161

Population and Community Studies

Type III Supracondylar humeral fracture in children treated by 3 lateral versus 2 cross K-wire fixation, Aden, Yemen
Abdulsalam Abdullah Hadi Mohsen, Nazih Ali Abdulrahman Omer, Mustafa Kamal Mustafa, Ahmed Mohamed Albushtra
[Abstract]
[pdf]
DOI: 10.5742/MEWFM.2022.9525164

Assessment of Premarital Screening for Prospective Couples in Aseer Region, Saudi Arabia, 2021
Ayman Mohammad Aboalam, Ali A. Al-Mousa, Saad Alamri, Ossama A. Mostafa
[Abstract]
[pdf]
DOI: 10.5742/MEWFM.2022.9525190

Review Articles

High sensitivity C-reactive protein and dyslipidemia as a marker for the risk for cardiovascular disease
Arun Pandeya, Naveen Kumar Shreevastva, Lal Chandra, Vishwajeet Rohil, Prahlad Karki, Madhab Lamsal
[Abstract]
[pdf]
DOI: 10.5742/MEWFM.2022.9525180

Role of Ipratropium bromide in management of Thunderstorm asthma
Numan Ahmad, Kaleem Murtaza Buttar
[Abstract]
[pdf]
DOI: 10.5742/MEWFM.2022.9525181

Subcutaneous Migration of Distal Ventriculoperitoneal Shunt Catheter in Morbidly Obese Patients: Two Case reports
Sara Aljohani, Khalid Mahrous, Ahmed AlJohani, Luma Qutub,
Layan Kutub, Raghad Alhajrasi, Hussam Kutub, Abdulrahman Mohammed AlAhmadi
[Abstract]
[pdf]
DOI: 10.5742/MEWFM.2022.9525183

Case Reports

A diagnostic surprise of Hodgkin's Lymphoma in a 29-year-old long distance runner
Kaleem Murtaza Buttar, Numan Ahmad
[Abstract]
[pdf]
DOI: 10.5742/MEWFM.2022.9525185

Middle age man with Gastroparesis
Babur Qayyum Khan
[Abstract]
[pdf]
DOI: 10.5742/MEWFM.2022.9525186

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Middle East Quality Improvement Program
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Chief Editor -
Abdulrazak Abyad MD, MPH, MBA, AGSF, AFCHSE
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Email: aabyad@cyberia.net.lb
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AUSTRALIA
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October 2022 - Volume 20, Issue 10

High sensitivity C-reactive protein and dyslipidemia as a marker for the risk for cardiovascular disease

Arun Pandeya (1)
Naveen Kumar Shreevastva (2)
Lal Chandra (3)
Vishwajeet Rohil (4)
Prahlad Karki (5)
Madhab Lamsal (6)

(1) Assistant Professor, Department of Biochemistry, Kathmandu Medical College, Basic Science Complex, Duwakot, Bhaktapur, Nepal.
(2) Assistant Professor, Department of Biochemistry, Faculty of Animal Science, Veterinary Science and Fisheries, Agriculture and Forestry University, Rampur, Chitwan, Nepal.
(3) Professor, Department of Biochemistry, Maulana Azad Medical College, New Delhi, India.
(4) Professor, Department of Clinical Biochemistry, Vallabhbhai Patel Chest Institute, University of Delhi, India.
(5) Professor, Department of Internal Medicine, BP Koirala Institute of Health Sciences, Dharan, Nepal
(6) Professor, Department of Biochemistry, BP Koirala Institute of Health Sciences, Dharan, Nepal.

Corresponding author:
Arun Pandeya,
Assistant Professor of Biochemistry,
Kathmandu Medical College, Basic Science Complex,
Duwakot, Bhaktapur, Nepal.
Email: arnpandey@gmail.com

Received: July 2022 Accepted: September 2022; Published: October 1, 2022. Citation: Arun Pandeya et al. High sensitivity C-reactive protein and dyslipidemia as a marker for the risk for cardiovascular disease. World Family Medicine. 2022; 20(10): 59-65. DOI: 10.5742/MEWFM.2022.9525180

Abstract

Background: High sensitivity C-reactive protein (hs-CRP), a sensitive marker of inflammation and tissue damage is an acute phase reactant. It is raised in hypertension and predicts cardiovascular outcome. Moreover elevated levels of inflammatory markers such as hs-CRP and altered lipid profile are commonly seen in hypertension which may develop cardiovascular events, hence, hs-CRP, lipid profile and nitric oxide (NO) have been incorporated in the study. The aims of this study were to find out a relationship of serum hs-CRP and dyslipidemia in hypertensives and to find out an association of serum hs-CRP with the risk for Cardiovascular disease (CVD). Methods: A case-control study was done among the patients visiting the outpatient department (OPD) of BP Koirala Institute of Health Sciences, Dharan, Nepal in which forty seven newly diagnosed hypertensives as cases and fifty age and sex matched healthy normotensives as controls, were enrolled in the study with the prior informed consent. hs-CRP, nitric oxide (NO) and lipid profile were estimated in both the cases and controls.

Results: Hypertensives have significantly raised levels of hs-CRP, non-high density lipoprotein cholesterol (non-HDL-C) and NO compared to that in controls (P< 0.05). hs-CRP has a significant positive correlation with systolic as well as diastolic blood pressure, BMI, and with triglyceride (TG) (P< 0.05). However, the correlation of hs-CRP with NO is negative but statistically significant (0.000).

Conclusion: The level of hs-CRP, which is thought to be a marker of inflammation, is significantly raised in hypertensives. Moreover, the majority of hypertensives are dyslipidemic suggesting hypertensives to be at an increased risk for the development of CVD.

Key words: Cardiovascular diseases, dyslipidemia, hs-CRP, hypertension, inflammation.







 


 
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