JOURNAL
Current Issue
Journal Archive
.............................................................
October 2020 -
Volume 18, Issue 10

View this issue in pdf format
........................................................
From the Editor

Editorial
A. Abyad (Chief Editor)
........................................................

 

Original Contribution

General Population Awareness Regarding Colorectal Cancer and its Determinants in Aseer region, Saudi Arabia
[Abstract]
[pdf]
Shehata Farag Shehata, Mohammed Saeed Alqahtani, Nawaf Ahmad Yahya, Abdullah Ali Aseeri, Mohammed Ali Alotaif, Abdulaziz Ali Abdullah
DOI: 10.5742MEWFM.2020.93868

Knowledge, attitudes and practices of school teachers regarding acute complications of type 1 diabetes mellitus in Abha city, southwestern Saudi Arabia
[Abstract]
[pdf]
Razan S. Al Humayed
DOI: 10.5742MEWFM.2020.93869

Knowledge, Attitude and Practices of Type 2 Diabetic patients attending a tertiary care hospital in Karachi
[Abstract]
[pdf]
Kanza Baig, Tafazzul Hyder Zaidi, Kiran Mehtab, Marium Farid, Shajeeya Khaliq, Wajiha Mukhtar, Shiza Tariq, Fozia Zaidi
DOI: 10.5742MEWFM.2020.93870

Prevalence and predictors of depression among medical students in Jeddah, Saudi Arabia
[Abstract]
[pdf]
Yousria Badawy, Areej Alsaggaf, Amani Bardi, Omnia Alganmi , Turki Alshehri
DOI: 10.5742MEWFM.2020.93871

Population and Community studies

Assessment of knowledge and practice of mothers regarding breastfeeding and contraception in the postpartum period in primary care centers, King Abdulaziz Medical City, Riyadh, Saudi Arabia
[Abstract]
[pdf]
Aida AlDughaither, Hadeel AlMutairi
DOI: 10.5742MEWFM.2020.93873

Family History of Cancer, Trend of Genetic Counselling and Screening in Karachi: A Survey among Students of Jinnah Sindh Medical University
[Abstract]
[pdf]
Nazish Jaffar, Syeda Ghadeer Zehra Naqvi, Rohma Momna, Maria Raza, Aliza Babar, Aliya Jafri
DOI: 10.5742MEWFM.2020.93874

Prevalence of primary headache among King Khalid University students in 2019
[Abstract]
[pdf]
Shehata Farag Shehata, Adnan Q. Al-Malki, Abdulrahman J. Alqahtani, Anas Ali Abo Tamraa, Ahmed Hussain Almutlaq, Ali Saad Alshamrani, Abdulelah Eed Alotaibi, Khalid Mohammed Alotaibi, Khalid Hussein Almutairi, Sultan Ali Alqahtani
DOI: 10.5742MEWFM.2020.93875

Perceptions of parents regarding polio vaccination in Karachi
[Abstract]
[pdf]
Hareem Arshad, Tafazzul Hyder Zaidi, Kiran Mehtab, Jibraeel Khan Durrani, Amna Anam, Ruqqiya Wahid, Aiman Nisar, Aroosa Hussain, Alia Mehboob, Shujaat Husain, Nadia Rubab Zaidi, Fozia Zaidi
DOI: 10.5742MEWFM.2020.93876

Awareness and Pattern of Utilizing Family Planning Methods in Married Women of Duwakot, Nepal
[Abstract]
[pdf]
Raut Binod, Kharel Sushil
DOI: 10.5742MEWFM.2020.93877

'A positive thing by mentioning it':
a qualitative study of experiences of brief physical health interventions for individuals diagnosed with severe mental illness in primary care
[Abstract]
[pdf]
Hassan Awan, Mohsin Allah Ditta, Mick McKeown, Karen Whittaker
DOI: 10.5742MEWFM.2020.93878

Difficulties facing family physicians in primary health care centers in Abha City, Saudi Arabia
[Abstract]
[pdf]
Hatim Mohammed Ali Alsharafi, Bassam Mousa Khalawy Mokali
DOI: 10.5742MEWFM.2020.93879

Remote consultations; what you need to know
[Abstract]
[pdf]
Rubena Ali Malik, Philip Sadler
DOI: 10.5742MEWFM.2020.93880

Bridging The Gap: A review of communication skills challenges for expatriate doctors in the Arabian Gulf
[Abstract]
[pdf]
Asif Parvez Malik, Ameer Muhammad Khan
DOI: 10.5742MEWFM.2020.9381

Review

Recognising depression in elderly patients in general practice
[Abstract]
[pdf]
Mohammed Ansary
DOI: 10.5742MEWFM.2020.93882

Case Report

CADASIL (Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy) in a young adult with migraine
[Abstract]
[pdf]
Mohammed Ansary
DOI: 10.5742MEWFM.2020.93883


Middle East Quality Improvement Program
(MEQUIP QI&CPD)

Chief Editor -
Abdulrazak Abyad MD, MPH, MBA, AGSF, AFCHSE
.........................................................

Editorial Office -
Abyad Medical Center & Middle East Longevity Institute
Azmi Street, Abdo Center,
PO BOX 618
Tripoli, Lebanon
Phone: (961) 6-443684
Fax:     (961) 6-443685
Email: aabyad@cyberia.net.lb
.........................................................

Publisher -
Lesley Pocock
medi+WORLD International
AUSTRALIA
Email: lesleypocock@mediworld.com.au
.........................................................

Editorial Enquiries -
abyad@cyberia.net.lb
.........................................................

Advertising Enquiries -
lesleypocock@mediworld.com.au
.........................................................

While all efforts have been made to ensure the accuracy of the information in this journal, opinions expressed are those of the authors and do not necessarily reflect the views of The Publishers, Editor or the Editorial Board. The publishers, Editor and Editorial Board cannot be held responsible for errors or any consequences arising from the use of information contained in this journal; or the views and opinions expressed. Publication of any advertisements does not constitute any endorsement by the Publishers and Editors of the product advertised.

The contents of this journal are copyright. Apart from any fair dealing for purposes of private study, research, criticism or review, as permitted under the Australian Copyright Act, no part of this program may be reproduced without the permission of the publisher.
October 2020 - Volume 18, Issue 10

Family History of Cancer, Trend of Genetic Counselling and Screening in Karachi: A Survey among Students of Jinnah Sindh Medical University

Nazish Jaffar (1)
Syeda Ghadeer Zehra Naqvi (2)
Rohma Momna (2)
Maria Raza (2)
Aliza Babar (2)
Aliya Jafri (3)

(1) MBBS, M.Phil.Assistant Professor, Department of Pathology, Jinnah Sindh Medical University, Karachi, Pakistan(2) MBBS, Jinnah Sindh Medical University, Karachi, Pakistan
(3) MBBS, MCPS, M.Phil, Assistant Professor, Department of Biochemistry, Jinnah Sindh Medical University, Karachi, Pakistan

Corresponding Author:
Dr. Syeda Ghadeer Zehra Naqvi
Jinnah Sindh Medical University
Cell: +92 3111819858
Email: syedaghadeerzehranaqvi@yahoo.com

Received: August 2020; Accepted:September 2020; Published: October 1, 2020. Citation: Nazish Jaffar et al. Family History of Cancer, Trend of Genetic Counselling and Screening in Karachi: A Survey among Students of Jinnah Sindh Medical University. World Family Medicine. 2020; 18(10): 55-61 DOI: 10.5742/MEWFM.2020.93874

Abstract

Background: Family history is a significant tool to identify at risk population. For cancer, about 22% positive family history has been reported which includes breast, ovarian, endometrial, prostate and colorectal carcinoma. Documentation of family history of cancer facilitates the decision of screening test and counselling in susceptible subjects.

The aim of the present study was to observe the trend of genetic counseling and screening tests in subjects with documented positive family history of cancers and to identify the knowledge of familial cancers and related hereditary mutations among MBBS, BDS and Pharm D students.

Methods: A cross sectional, questionnaire-based survey was conducted at Jinnah Sindh Medical University from June to September 2019. A total of 162 MBBS, BDS and PHARM D students were included in the study. Data were analyzed by SPSS version 22.

Result: Approximately 42(25.9%), 67(41.4%) and 60(37.0%) participants had positive family history of cancer in first, second- and third-degree relatives, respectively. Most commonly reported familial malignancy 45(27.8%) was breast carcinoma. BRCA gene screening and mammography was prescribed to 6(3.7%) and 20(12.3%) subjects respectively with positive familial history of breast cancer. Family history of hereditary nonpolyposis colorectal carcinoma was positive in 16(9.9%). However, colonoscopy was prescribed to 7(4.3%) subjects. About 44(27.2%) subjects reported documentation of family history and 36(22.2%) of participants were advised genetic counselling or referred to a genetic counsellor (p= 0.000). Students of MBBS were more aware of familial cancers and hereditary mutations in comparison to dentistry and pharmacy students.

Conclusion: The most common reported familial malignancy was breast carcinoma and the least frequent was retinoblastoma. Documentation of family history of cancer, advised screening and genetic counselling was found to be inadequate in our clinical setup. Students of MBBS had a good knowledge of familial cancer and related hereditary mutations in comparison to dentistry and pharmacy students.

Key words: cancer; family history; screening; genetic counselling; documentation.

 







 


 
.................................................................................................................