From
the Editor
This is the eighth issue
this year that has various papers from the region
plus a special education section on surgery.
Al Nyazee A.A.Q et al; stressed that human
papillomavirus (HPV) infection was the criminalized
in cervical cancer. The authors attempted to
answer is there any new genome responsible for
the cervical cytological changes other than
the known high risk human papilloma virus gens.
In addition the authors want to raise the awareness
about HPV and cervical cancer for motivation
and draw attention to make more studies about
this subject.
They followed a cross sectional study with a
convenient sample of 188 females, information
was obtained by interviewing the patient. Pap
smear done for all patients, HPV screening,
and genotyping test done for 151 patient. Positive
HPV Pap smear (Positive HPV Pap) found in 31
(16.5%) patients, while (Positive HPV test)
found among 4 cases (2.7%). Negative HPV test/
Positive HPV Pap found among 31 (20.5%). Three
HPV gens was detected HPV (16, 18, 65), 2 (50%),
1 (25%), 1 (25%), respectively. The mean age
for those had Negative HPV test/ Positive HPV
Pap (33.5±8.3), was significantly lower
than those had Positive HPV test/ Negative HPV
Pap (38.8 ±11.1), and those (Negative
HPV/Positive HPV Pap) found among 31 (20.5%).
The authors concluded that heterogeneity was
common among Iraqi patient, decrease with increasing
age. Results suggest presence of new genotype.
Kharel S & Mandira M; et al attempted to
know the extent of impairment of lung function
in diabetics among urban population around Sinamangal,
Kathmandu. To know the variations in the values
of the forced vital capacity (FVC) , peak expiratory
flow rate (PEFR), forced expiratory volume in
the first second (FEV1), and FEV1/FVC percentage
among Type 2 Diabetes Mellitus and non-diabetic
healthy population. A cross-sectional study
was conducted at Kathmandu Medical College,
Nepal from September 2018 to February 2019.
Adult males, 105 with DM and 105 non-DM healthy
matched subjects were enrolled for this study.
The results showed that mean FVC, FEF25-75,
FEV1, FEV1/FVC% and PEFR were found to be significantly
lower in patients with Type 2 DM as compared
to non-DM; there were significant differences
between mean PFT values among diabetics and
non-diabetics (P < 0.05). The authors concluded
that lungs are affected in patients of diabetes
and pulmonary function test should be performed
in diabetics in order to prevent further complications
which will definitely help in maintaining quality
of life.
Helvaci MR et al ;tried to understand whether
or not there is a significant relationship between
smoking and plasma triglycerides values. The
study included 457 cases. Patients with plasma
values of triglycerides lower than 100 mg/dL
were collected into the first, lower than 150
mg/dL into the second, lower than 200 mg/dL
into the third, and 200 mg/dL or higher into
the fourth groups, respectively. The mean ages
of the groups, body mass index (BMI), and low
density lipoproteins increased just up to the
plasma triglycerides value of 200 mg/dL, significantly
(p<0.05 for all). On the other hand, the
mean fasting plasma glucose and prevalences
of white coat hypertension, hypertension, diabetes
mellitus, and chronic obstructive pulmonary
disease increased parallel to the plasma triglycerides
values from the first towards the fourth groups,
gradually. As one of the most surprising results,
prevalence of smoking also increased parallel
to the plasma values of triglycerides from the
first towards the fourth groups, gradually (16.3%
versus 42.5%, p<0.001). The authors concluded
that plasma triglycerides may actually be some
acute phase reactants indicating the disseminated
endothelial damage, inflammation, fibrosis,
and eventual atherosclerosis all over the body.
There may be highly significant relationships
between plasma triglycerides values and aging,
BMI, and smoking up to the plasma triglycerides
value of 200 mg/dL, but smoking may be much
more important for plasma triglycerides values
of 200 mg/dL or greater.
Omer S et al; stressed that There is a rising
trend in breast diseases worldwide. The incidence
of breast cancer is increasing in the developing
country due to increase life expectancy, increase
urbanization and adoption of western lifestyle,
lack of population awareness, delayed health
seeking behavior and low levels of female education.
Retrospective study of breast specimens from
354 women was taken from the private modern
histology lab and Ibn Sina lab in Aden; between
2006- 2013. The data were collected from the
referral sheet. All women with breast cancer
underwent Fine Needle Aspiration Cytology (FNAC)
or/and biopsy due to the presence of breast
cancer for the purpose of diagnosis were included.
The results show 44% of the cases was from IBB
Governorate, followed by cases from Aden 33%.
The age of the women with breast cancers was
range from 20 years (youngest patient) to 87
years (oldest patient) with a mean of 46.9 ±
12 years. 56.2% of lumps were in the right breast.
Left breast was the next common (41.3%). 3.5%
of the cases affecting the both breasts at the
time of diagnosis. Overall pattern of breast
cancer invasive ductal carcinoma was the commonest
finding (57.5%) followed by invasive lobular
carcinoma (20%), in situ ductal carcinoma (13.2%)
and in situ lobular carcinoma. (3.4%). the less
frequent subtypes were, Malignant phyllodes
represented (2.3%). Papillary carcinoma, Medullary
carcinoma and Mucinous carcinoma were (1.1%)
each respectively. The authors concluded that
malignant neoplastic breast lesions were seen
beyond 4th decade. Invasive carcinoma was the
most common malignant tumor among Yemeni women.
Chief Editor:
A. Abyad
MD, MPH, AGSF, AFCHSE
Email: aabyad@cyberia.net.lb
.........................................................................................................................
|