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September 2021 -
Volume 19, Issue 9


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From the Editor

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Incidence prevalence and management of different types of arrhythmia in patients with ischemic heart disease in Taif city
Ali M. AlabdaliMohammed N. Elganainy, Waad S. Alzahrani,
Abdulelah A. Asiri, Hanan R. Alhuthali, Hussain S. Alqahtani, Danah K. Kabrah
[pdf]
[Abstract]
DOI: 10.5742/MEWFM.2021.94118


Knowledge, Attitude and Practice Toward the Use of Emergency Contraception Methods Among Women in the Kingdom of Saudi Arabia
Rehab Alsaleh, Nouf Khaleel Althagafi, Siba Nasser Algaidy, Noura Ali Alhasawi, Raffal Abdulwahab Algaedy
[pdf]
[Abstract]
DOI: 10.5742/MEWFM.2021.94119

Knowledge, attitude and practice towards heat related illnesses of the general public of Jeddah, Saudi Arabia
Fathi El-Gamal, Ahmed Ghandoura, Abdullah Alammari, Bushra Alghamdi,
Lama Babhair, Sali alsabhani
[pdf]
[Abstract]
DOI: 10.5742/MEWFM.2021.94120

Intertrochanteric Fracture Treated by Dynamic Hip Screw, Aden, Yemen
Abdulsalam Abdullah Hadi Mohsen
[pdf]
[Abstract]
DOI: 10.5742/MEWFM.2021.94122

Regional Covid Issues

Essentials to prevent and live with COVID-19: An Explanatory Mixed Method Study at Bisha, Kingdom of Saudi Arabia
Muffarah Hamid Alharthi
[pdf]
[Abstract]
DOI: 10.5742/MEWFM.2021.94123

Anxiety and Perceived Stress among Physicians Working at Cairo University Hospitals Amid COVID-19 Pandemic
Eman Elsayed Sedik Ebrahim, Marwa Mostafa Ahmed, Dalia Mohamed Gaber,
Heba Galal Elnahas
[pdf]
[Abstract]
DOI: 10.5742/MEWFM.2021.94125

Review

Semaglutide for the treatment of obesity - a review
Abubakar Bham, Mohsin Allah Ditta
[pdf]
[Abstract]
DOI: 10.5742/MEWFM.2021.94116

Population and Community Studies

Burden of hypothyroidism in the primary care population in Qatar
Sabana Shaikh, Prince Christopher Rajkumar Honest
[pdf]
[Abstract]
DOI: 10.5742/MEWFM.2021.94126

Knowledge, Attitudes, and Practice of mothers toward permanent and temporal contraindications of Breast Feeding in Taif city, Saudi Arabia
Manal El Nashar, Atheer Mohammed Al-fuhayd, Razan Abadel Algethami,
Abeer hammad Alharthi, Huda Abdullah Alessa, Areej mohmammed Abdullah
[pdf]
[Abstract]
DOI: 10.5742/MEWFM.2021.94129

Middle East Quality Improvement Program
(MEQUIP QI&CPD)


Chief Editor -
Abdulrazak Abyad MD, MPH, MBA, AGSF, AFCHSE

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Publisher -
Lesley Pocock
medi+WORLD International
AUSTRALIA
Email
: lesleypocock@mediworld.com.au
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September 2021 - Volume 19, Issue 9

Semaglutide for the treatment of obesity – a review

Corresponding author:
Dr Abubakar Bham, General Practitioner,
Gloucester, United Kingdom
Email: abham@doctors.org.uk

Received: August 2021; Accepted: August 2021; Published: September 1, 2021. Citation: Abubakar Bham, Mohsin Allah Ditta. Semaglutide for the treatment of obesity – a review. World Family Medicine. 2021; 19(9): 61-64 DOI: 10.5742/MEWFM.2021.94116

 

Abstract

Increasing rates of obesity and its comorbidities continue to place a burden on individuals and health systems. Lifestyle interventions, although effective, are not always successful in long term management. The use of existing medicinal strategies, such as sibutramine and orlistat have not been very successful due to their own limitations. Semaglutide is a glucagon-like peptide-1 analogue that has been utilized in type 2 diabetes mellitus treatment. Its use in weight management has been recently explored in several studies. A review of literature can provide insight into whether semaglutide is a potential avenue for long term and sustainable weight loss. All studies reviewed identified that study participants on semaglutide experienced a significantly higher overall weight loss than placebo and most other comparison treatments. There were gastrointestinal adverse events recorded in most studies, but these did not seem to have an impact on the overall weight loss. Semaglutide provides a promising avenue for weight loss in obese and overweight individuals, although further research on management avenues for the GI events may ensure long term and sustained use.

Key words: semaglutide, obesity, weight loss







 


 

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