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                   Antibiotics: 
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                    Velocity 
                    and Elasticity Curves of Pregnancy Wastage and Caesarian Deliveries 
                    in Bangladesh
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                |  | 
  Abdulrazak 
                    Abyad 
                    MD, MPH, MBA, AGSF, AFCHSE
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                                  | Velocity 
                                      and Elasticity Curves of pregnancy wastage 
                                      and Caesarian Deliveries in Bangladesh |   
                                  |  |   
                                  |  |  
                                 
                                  | 
                                       
                                        | Md. Atikur Rahman 
                                            Khan1, Sumaiya Abedin1, Md. Nazrul 
                                            Islam Mondal1, and Md. Mostafizur 
                                            Rahman2 Institution:1Department of Population Science 
                                            and Human Resource Development, University 
                                            of Rajshahi, Rajshahi-6205, Bangladesh.
 2Department 
                                            of Planning and Statistics, Xiamen 
                                            University, Fujian, China.
 |  
 
                                       
                                        | ABSTRACT The aim of this paper 
                                            is to investigate the effect of age 
                                            of mothers as a cause of pregnancy 
                                            wastage and delivery types. Using 
                                            the information from 2967 mothers 
                                            from Rajshahi District within the 
                                            reproductive span (15-49 years), we 
                                            have found that the proportion of 
                                            pregnancy wastage to live births in 
                                            two ages of reproductive years is 
                                            tremendously dodgy whereas in other 
                                            age groups, between 20 and 35, these 
                                            are comparatively benign. Further, 
                                            6717 births were studied to investigate 
                                            the flow of caesarian deliveries over 
                                            the ages. We found 359 caesarian deliveries 
                                            against 6,358 natural (vaginal) deliveries. 
                                            Some statistical tools were used and 
                                            the velocity and elasticity curves 
                                            were drawn to analyze the risk of 
                                            pregnancy wastage and caesarian deliveries. 
                                            Our result shows that the risk of 
                                            caesarian delivery increases with 
                                            an increased age and this risk expands 
                                            with age.
 Keywords and phrases: 
                                            Pregnancy wastage, Caesarian delivery, 
                                            Vaginal delivery, Velocity curve, 
                                            Elasticity curve, and Polynomial regression.
 |  
 Pregnancy 
                                      is a female state that is produced due to 
                                      the implantation of the fertilized ovum 
                                      in the uterine endometrium and ultimately 
                                      giving rise to a foetus; and pregnancy wastage 
                                      is the loss of product of conception normally 
                                      or therapeutically (Jeffcoate, 1975). Pregnancy 
                                      wastage can be classified as intra-uterine 
                                      foetal death, abortion, and menstrual regulation 
                                      (Jeffcoate, 1975; and Shaw, Soutter and 
                                      Stanton 2003). In our study, we have dealt 
                                      with the normal pregnancy wastage that is 
                                      not therapeutic. 
 Every 
                                      year about eight million women suffer from 
                                      pregnancy related complications and over 
                                      half a million die. About 99% of these are 
                                      in developing countries (WHO, 2004). Most 
                                      of these deaths can be averted even where 
                                      resources are limited. The poor reproductive 
                                      health of women, in third world countries, 
                                      is an outcome of the general neglect of 
                                      health and nutrition in childhood and adolescence, 
                                      which affects their future well being (De 
                                      Silva, 1998). In 1987 Ardebili, Kamali, 
                                      Pouranssari and Komarizadeh studied the 
                                      reproductive behaviour of 1525 pregnant 
                                      women. The type of pregnancy termination 
                                      that resulted in live birth or abortion 
                                      has a significant relationship to the age 
                                      of the mother. Again, the highest percentage 
                                      of abortion was observed in (15-19) age 
                                      group and the highest number of natural 
                                      deliveries was observed in the age group 
                                      (20-29). 
 Khandait 
                                      et al (2000) examined complications of the 
                                      reproductive health of married women and 
                                      envisaged the age factor as a cause of stillbirth, 
                                      accumulating with other factors. Yasakawa 
                                      and Tayahashi (1990) observed that the age-specific 
                                      maternal mortality was rising with age. 
                                      They also investigated that pregnant women 
                                      aged over 35 faced more pregnancy complications 
                                      with high risk. Another study by Breart, 
                                      Blondel, and Maillard (1987) acclaimed with 
                                      the risks of late pregnancy for mothers 
                                      and their births indicated that there was 
                                      excess risk for mothers over age 35 but 
                                      the difference is decreasing relative to 
                                      the general population (mothers before 35). 
                                      They also found that the risk of mothers 
                                      over 34 was 3.6 times higher in 1975 and 
                                      2.6 times higher in 1983 than for the general 
                                      population. Study on scheduled caste women 
                                      of Punjab experienced the least number of 
                                      abortion and stillbirths in the age group 
                                      (25-29) and the risk of pregnancy wastage 
                                      increases with age (Sidhu and Sidhu, 1988). 
                                      Similar results by Banerjee and Hazra (2004) 
                                      showed that the rates of pregnancy wastage 
                                      in two extreme age groups (<20 and 35+) 
                                      are relatively higher. This evidences indicates 
                                      that there exists an age-specific relationship 
                                      of pregnancy wastage and mothers' age. 
 Further, 
                                      Kim, Byun, and Lee (1991) studied over 2874 
                                      mothers and observed 342 caesarian deliveries 
                                      against 2532 vaginal deliveries. They included 
                                      several factors like, education, occupation, 
                                      residence (big cities, urban, and rural) 
                                      and age of mother at birth to explain the 
                                      delivery status. As to the mothers age at 
                                      delivery they found that 10.4% of C-section 
                                      (caesarian sections) were under age 24, 
                                      12.1% were in (25-29), and 14.1% were over 
                                      30. Thus, there is an increasing trend of 
                                      C-section with age. But, the exact relationship 
                                      of pregnancy wastage and caesarian deliveries 
                                      with respect to their flows over the age 
                                      of the mother, is still unknown. In this 
                                      paper, an attempt has been made to investigate 
                                      the age-specific flow of pregnancy wastage 
                                      and caesarian delivery.
 
 DataThe data were collected from a field survey 
                                      conducted in the district of Rajshahi of 
                                      Bangladesh. We collected information from 
                                      2967 mothers by preparing an open-ended 
                                      questionnaire. Also, the delivery status 
                                      of 6717 births were under investigation 
                                      and our data evaluated only the delivery 
                                      types (caesarian and vaginal).
 
 MethodsIn this paper we have used the logic of 
                                      equilibrium level of satisfaction, velocity 
                                      and elasticity curves. The logic of equilibrium 
                                      has been extensively using in the field 
                                      of economics especially in demand analyses. 
                                      The concept of velocity has a greater applicability 
                                      to the physical sciences and recently it 
                                      has been used in human biology. On the other 
                                      hand, elasticity of goods, demand and income 
                                      elasticity, explain the speed of relative 
                                      change and replacement (Varian, 2003; Chakravarty, 
                                      1997 and Dewett and Chand, 1999).
 
 Equilibrium level 
                                      of satisfactionEquilibrium level of satisfaction leads 
                                      to the intersection of two curves at a particular 
                                      point. When one curve is downward sloping 
                                      and the other is going upward from the origin, 
                                      then both the curves intersect each other 
                                      at a particular point. At that point values 
                                      on both the curves are equal. For example, 
                                      if we consider a demand and a supply curve. 
                                      Then the equilibrium level of demand and 
                                      supply attains at the point of their intersection 
                                      (Varian, 2003, Chakravarty, 1997 and Dewett 
                                      and Chand, 1999).
 
 Velocity curveTo draw the velocity and elasticity curves 
                                      we fit the polynomial regression models. 
                                      The velocity curve is just the first derivative 
                                      of the fitted polynomial regression line 
                                      with respect to age (Gasser et al., 1984; 
                                      Ali and Ohtsuki, 2001; Islam et al., 2003). 
                                      The polynomial regression model of order 
                                      'p' (Gujarati, 1995 and Montegomery and 
                                      Peck, 1982) is of the form:
 
 where all the parameters 
                                      ( ) and the error terms (u) follow the usual 
                                      assumptions.Now, the velocity curve is just the first 
                                      derivative of the above equation and so 
                                      we get
 
  
 |  | Elasticity curveThe elasticity can be computed using the 
                                      formula mentioned by Dewett and Chand (1999), 
                                      Chakravarty (1997) and Varian (2003) as
 
 We can comment on the 
                                      speed of relative change or replacement 
                                      using the following criterion:  
                                       
                                        | (a) | if  then the overall process is inelastic, |   
                                        | (b) | if  then the process is elastic and the 
                                          speed of relative change is negative, 
                                          that is, speed of change of y is slower 
                                          than x, |   
                                        | (c) | if  then the process is elastic and the 
                                          speed of relative change is positive, 
                                          that is, the values of y increases faster 
                                          than x, |   
                                        | (d) | if  then the relative change is proportionate 
                                          to each other and in this case both 
                                          the factors change equally likely. |  Cross validity predictive 
                                      powerThe cross validity predictive power has 
                                      been used to examine the rigidity of the 
                                      fitted polynomial regression models. The 
                                      cross validity predictive power due to Stevens 
                                      (1996) and Khan and Ali (2003) is
 
 
  where R2 is 
                                      the coefficient of multiple determination, 
                                      n is the sample size, k is the number of 
                                      regressors used in the model. Further, the 
                                      stability of R2(Stevens, 1996, 
                                      Khan and Ali, 2003, Islam et al., 2003) 
                                      can be computed as: First 
                                      of all, we simply present the observed values, 
                                      computed proportions (Table 1) and smoothed 
                                      proportions (Table 2) both for urban and 
                                      rural areas. The proportion of pregnancy 
                                      wastage to live birth is calculated by dividing 
                                      the number of pregnancy wastage by the number 
                                      of live birth in a specific age group. Similarly, 
                                      proportion of pregnancy wastage to mother 
                                      and that of caesarian deliveries to vaginal 
                                      deliveries (Table 
                                      1) have been computed. Our aim is 
                                      to know the age-specific flow of pregnancy 
                                      wastage and caesarian deliveries. So, we 
                                      have used smoothing techniques, "4253H, 
                                      twice" from Minitab window 12.0 to 
                                      obtain the smoothed values (Table 
                                      2). 
 Plotted smoothed proportions 
                                      (Fig.1) 
                                      intersect each other at a certain point 
                                      and at this point equilibrium status is 
                                      achieved. We observe that for rural areas, 
                                      pregnancy wastage to live birth and to mother, 
                                      is equal at age 23. But, in urban areas 
                                      this is at age 25. At these points proportion 
                                      of pregnancy wastage to live birth and to 
                                      mother are equal, that is, number of live 
                                      birth equals number of mother. In other 
                                      words, at that point every mother yields 
                                      a live birth with minor risk of pregnancy 
                                      wastage. 
 A matter of regret is that for delivery 
                                      status much data for different age groups 
                                      especially the last two age groups, are 
                                      not available for urban and rural areas 
                                      separately. Thus, we were compelled to conduct 
                                      our study combining urban and rural areas 
                                      together.Consequently, we have nested our 
                                      focus on equilibrium level for proportion 
                                      of pregnancy wastage to live birth and proportion 
                                      of caesarian deliveries to vaginal deliveries. 
                                      At age 25 this equilibrium level is achieved. 
                                      Thus, at 25 years of mother
  , 
                                      that is, for non-zero pregnancy wastage 
                                      (Pw), Live birth (Lb), and Vaginal delivery 
                                      (Vd) we have caesarian delivery  that explains the minor risk of pregnancy 
                                      wastage and live birth reduces the risk 
                                      of caesarian deliveries. Elaborately, we 
                                      can say that live birth and vaginal deliveries 
                                      are fixed at certain non-zero level then 
                                      increase (or minor risk) of pregnancy wastage 
                                      yield increases (or minor risk) of caesarian 
                                      delivery. Similarly, if pregnancy wastage 
                                      and vaginal delivery is fixed at certain 
                                      non-zero levels then the increase of live 
                                      birth substantially reduces the risk of 
                                      caesarian delivery. Moreover, we can say 
                                      that if a woman gives a live birth vaginally 
                                      then the risk of caesarian delivery for 
                                      the next birth is very low. Here it is mentionable 
                                      that these comments are valid only if such 
                                      equilibrium condition is achieved. Thus, 
                                      our findings elucidate that the women at 
                                      age 25 in Bangladesh bears low risk for 
                                      child bearing with respect to less risk 
                                      of both pregnancy wastage and caesarian 
                                      deliveries. To check the liability of our 
                                      results we formed a control group that includes 
                                      all the respondents of age 25 years. Then 
                                      we performed a study over every single year. 
                                      One caveat that we faced was availability 
                                      of data in every single year; especially 
                                      the information on birth and delivery types 
                                      for respondents after 35 years of age was 
                                      really shaky. However, we did it for those 
                                      single year's respondents to whom data were 
                                      available. To accumulate the joint effect 
                                      of both factors (pregnancy wastage and caesarian 
                                      delivery) we added the proportion of pregnancy 
                                      wastage to live birth and proportion of 
                                      caesarian delivery to vaginal delivery for 
                                      every single year. We found that this was 
                                      the lowest at the single age year 25 and 
                                      was 0.0524. Thus, we may assure that our 
                                      results related to the equilibrium level 
                                      of age (25 year) are true. 
 Thereafter, 
                                      we fitted statistical models to those smoothed 
                                      proportions and found that third order polynomial 
                                      regression model better explains the age-specific 
                                      flow of both pregnancy wastage and caesarian 
                                      deliveries. Our fitted models are highly 
                                      stable (Table 
                                      3). Further, the velocity and elasticity 
                                      of caesarian deliveries and pregnancy wastage 
                                      (Table 
                                      4) have been computed. 
 Velocity curves in (Fig. 
                                      3) show that velocity of pregnancy 
                                      wastage to live birth both in urban and 
                                      rural areas yield negative magnitude but 
                                      that of caesarian deliveries yield positive 
                                      magnitude. Thus, we can say that the pregnancy 
                                      wastage decreases over ages whereas caesarian 
                                      delivery increases. Elasticity of pregnancy 
                                      wastage to live birth is less than unity 
                                      up to the age 30 and thereafter these values 
                                      lie between -1 and +1, that is, up to age 
                                      30 the system is elastic and inelastic thereafter 
                                      (Table 
                                      4). In other words, the risk of 
                                      pregnancy wastage decreases with the increase 
                                      of age and the speed is faster than the 
                                      speed of age. However, the pregnancy wastage 
                                      to live birth in urban areas is almost inelastic 
                                      (Fig.4). But, for caesarian deliveries the 
                                      elasticity is always greater than one and 
                                      so the risk of caesarian deliveries increase 
                                      with the increase of age (Fig.4). 
                                      Furthermore, the risk of caesarian delivery 
                                      (speed) increases faster than the increase 
                                      of age.
  Risk of pregnancy wastage 
                                      and caesarian deliveries change with age. 
                                      Increased age increases the risk of caesarian 
                                      delivery, but decreases the risk of pregnancy 
                                      wastage. However, in the extreme age groups 
                                      pregnancy wastages are observed substantially 
                                      larger. Equilibrium condition for risk of 
                                      pregnancy wastage and caesarian delivery 
                                      yields 25 year as an ideal age of child 
                                      bearing for Bangladeshi women, as both the 
                                      risks are in tolerable situations. Therefore, 
                                      no pregnancy before 25 and only one birth 
                                      at this age can avail of acceptable risks 
                                      of pregnancy wastage and caesarian delivery 
                                      in Bangladesh. Different country and regional 
                                      differences may draw different risks and 
                                      age structure for pregnancy wastage and 
                                      caesarian deliveries. Early marriage (before 
                                      18 years) and teenage motherhood is a stark 
                                      reality behind the plight of female health 
                                      hazards in Bangladesh. A proper policy towards 
                                      safe motherhood (no birth before 25 years) 
                                      may be helpful to overcome the pregnancy 
                                      related deficiencies as well as to control 
                                      the population growth to a large extent. A part of this research 
                                      has been conducted under a project financed 
                                      by the UNFPA. The authors thankfully acknowledge 
                                      the Project Director, Dr. J. A. M. S. Rahman 
                                      for partial support of our research work. 
                                      We are also thankful to the participants 
                                      of our seminar for their valuable suggestions. 
                                      Last but not least, our sincere gratitude 
                                      to the comments from anonymous reviewers 
                                      for increasing the rigidity of our paper. |   
                                  |  |   
                                  | 
                                       
                                        | Fig. 
                                          1: Smoothed proportion of pregnancy 
                                          wastage to live birth and to mother |  
 Here PwLbU and PwLbR 
                                      represent pregnancy wastage to live birth 
                                      for urban and rural areas; PwMU and PwMR 
                                      refer to pregnancy wastage to mother both 
                                      for urban and rural areas, respectively. << 
                                      back to text 
                                       
                                        | Fig. 
                                          2: Equilibrium level of pregnancy wastage 
                                          and caesarian deliveries |  
 Here PwLb and Caesarian 
                                      represent proportion of pregnancy wastage 
                                      to live birth and that of caesarian deliveries 
                                      to vaginal deliveries, respectively. << 
                                      back to text 
                                       
                                        | Fig. 
                                          3: Velocity of pregnancy wastage and 
                                          caesarian deliveries |   
 Here Caesar indicates 
                                      caesarian deliveries. All other notations 
                                      are same as in Fig.1.
 << 
                                      back to text
 
                                       
                                        | Fig.4: 
                                          Elasticity of pregnancy wastage and 
                                          caesarian deliveries |  
 Here RLB, and ULB indicate 
                                      elasticity of pregnancy wastage to live 
                                      birth in rural and urban areas, and C stands for elasticity of caesarian 
                                      deliveries in total (urban and rural) areas.
 << 
                                      back to text  
 
                                       
                                        | Table 
                                          1: Pregnancy wastage to mother and live 
                                          birth |  
                                       
                                        |  | Urban | Rural | Urban & rural |   
                                        | Observed Values | Observed Values | Observed Values |   
                                        | Age | Birth | Pw | M | PwLb | PwM | Birth | Pw | M | PwLb | PwM | V | C | Cv |   
                                        | 15-20 | 21 | 2 | 45 | 0.095238 | 0.044444 | 72 | 8 | 149 | 0.111111 | 0.053691 | 2062 | 51 | 0.024733 |   
                                        | 20-25 | 203 | 12 | 202 | 0.059113 | 0.059406 | 341 | 22 | 319 | 0.064516 | 0.068966 | 2297 | 132 | 0.057466 |   
                                        | 25-30 | 388 | 23 | 324 | 0.059278 | 0.070988 | 601 | 28 | 351 | 0.046589 | 0.079772 | 1296 | 94 | 0.072531 |   
                                        | 30-35 | 523 | 32 | 324 | 0.061185 | 0.098765 | 566 | 30 | 261 | 0.053004 | 0.114943 | 481 | 49 | 0.101871 |   
                                        | 35-40 | 519 | 34 | 277 | 0.065511 | 0.122744 | 598 | 21 | 229 | 0.035117 | 0.091703 | 164 | 24 | 0.146341 |   
                                        | 40-45 | 446 | 29 | 191 | 0.065022 | 0.151832 | 404 | 17 | 141 | 0.042079 | 0.120567 | 54 | 8 | 0.148148 |   
                                        | 45-49 | 268 | 17 | 107 | 0.063433 | 0.158879 | 170 | 7 | 47 | 0.041176 | 0.148936 | 4 | 1 | 0.25 |   
                                        | Total | 2368 | 149 | 1470 |  |  | 2752 | 133 | 1497 |  |  | 6358 | 359 |  |   Here Pw, M, PwLb, PwM, 
                                      V, C, and Cv indicate Pregnancy wastage, 
                                      Mother, Proportion of pregnancy wastage 
                                      to live birth, Proportion of pregnancy wastage 
                                      to mother, Vaginal delivery, Caesarian delivery, 
                                      and Proportion of caesarian delivery to 
                                      vaginal delivery, respectively. << 
                                      back to text
 
                                       
                                        | Table 
                                          2: Smoothed proportion |  
                                       
                                        | AGE | Urban | Rural | Urban & rural | Urban & rural |   
                                        |  | PwLb | PwM | PwLb | PwM | PwLb | Caesarian to vaginal |   
                                        | 15-20 | 0.078165 | 0.044444 | 0.105083 | 0.053691 | 0.091624 | 0.024733 |   
                                        | 20-25 | 0.069348 | 0.059143 | 0.071963 | 0.067360 | 0.070656 | 0.051604 |   
                                        | 25-30 | 0.064310 | 0.076591 | 0.051199 | 0.080151 | 0.057755 | 0.077014 |   
                                        | 30-35 | 0.063146 | 0.098643 | 0.042820 | 0.093503 | 0.052983 | 0.10428 |   
                                        | 35-40 | 0.063337 | 0.123023 | 0.041145 | 0.108585 | 0.052241 | 0.135726 |   
                                        | 40-45 | 0.063433 | 0.143879 | 0.041347 | 0.126115 | 0.05239 | 0.180715 |   
                                        | 45-49 | 0.063433 | 0.158879 | 0.041176 | 0.147056 | 0.052304 | 0.246312 |  Notations are explained in 
                                      Table 1. << 
                                      back to text
 
                                       
                                        | Variables | Fitted Models | R2 | CVPP | Stability |   
                                        | Urban | Pregnancy wastage to live birthPregnancy wastage to mother |   | 0.99980.9997 | 0.99880.9983 | 0.00100.0014 |   
                                        | Rural | Pregnancy wastage to live birthPregnancy wastage to mother |   | 0.99970.9999 | 0.99830.9994 | 0.00140.0005 |   
                                        | Both | Caesarian 
                                          deliveries to live birth |   | 0.9998 | 0.9988 | 0.0010 |  << 
                                      back to text
 
                                       
                                        | Table 
                                          4: Velocity and elasticity of pregnancy 
                                          wastage and caesarian delivery |  
                                       
                                        | Age | Velocity | Elasticity |   
                                        | PwLb | Cv | PwLb | Cv |   
                                        | Rural | Urban | Urban & Rural | Rural | Urban | Urban 
                                            and Rural |   
                                        | 15-20 | -0.00851 | -0.002327 | 0.006463 | -1.4141 | -0.52079 | 4.665101 |   
                                        | 20-25 | -0.00522 | -0.001331 | 0.005073 | -1.64836 | -0.43254 | 2.165553 |   
                                        | 25-30 | -0.00271 | -0.000596 | 0.004808 | -1.44058 | -0.25358 | 1.715809 |   
                                        | 30-35 | -0.00098 | -0.000122 | 0.005668 | -0.74046 | -0.06274 | 1.789762 |   
                                        | 35-40 | -1.57E-05 | 9.14E-05 | 0.007653 | -0.01449 | 0.054272 | 2.111322 |   
                                        | 40-45 | 0.000172 | 4.34E-05 | 0.010763 | 0.176498 | 0.028944 | 2.517524 |   
                                        | 45-49 | -0.00041 | -0.000266 | 0.014998 | -0.47722 | -0.19916 | 2.897614 |  Notations are explained in 
                                      Table 1. << 
                                      back to text |   
                                  | 
 |   
                                  |  |   
                                  | 
                                       
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