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August 2021 -
Volume 19, Issue 8


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From the Editor

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Primary Health Care in Pandemics: Barriers, Challenges and Opportunities
Tawfik A M Khoja, Waris Qidwai, Salman Rawaf, Faisal A Alnaser, Kashmira Nanji, Abdullah T Khoja, Nabil Yasin Al Kurashi, Nagwa Eid Sobhy Saad, Wafa Halasa, Taghreed M Farahat, Mohammed Al Shafaee, Mariam Al Shetti, Muntazar Bashir, Wadeia Alsharief, Rihab AlWotayan, Saied Alimky, Huda al-duwaisan
[pdf]
[Abstract]
DOI: 10.5742/MEWFM.2021.94090

Effect of the COVID-19 pandemic on career perceptions among medical students in (IMSIU)
Abdulmalk Abdullah Almadhi, Abdulaziz H Alhorishi, Abdullah Z Alnamshan, Faris A Alkhamis, Ruba S Alosaimi, Turki Y Alassaf, Fahad A Alateeq
[pdf]
[Abstract]
DOI: 10.5742/MEWFM.2021.94091

Public willingness to receive COVID-19 vaccine in Saudi Arabia
Abdulrahman Alamri, Noura Ali Alshahrani, Alaa Abdulrahman Al Bakita, Anhar saud alqahtani, Jamilah Hassan Aldaleel Alshahrani, Maram saad Alshahrani
[pdf]
[Abstract]
DOI: 10.5742/MEWFM.2021.94092

Original Contribution

A Multicenter Cross-sectional Study to Assess the Knowledge of Oral Health Problems Among Diabetes Patients in Saudi Arabia
Afnan A. Malibari, Mariann H. Al-Jehani, Dareen A. Qattan, Noor S. Alharbi, Morooj H. Alharbi, Hanan S. Bin Yahib, Abdullah M Alzahrani
[pdf]
[Abstract]

DOI: 10.5742/MEWFM.2021.94093

Prevalence and Co-occurrence of Major Depression and Generalized Anxiety Disorders Among Adolescents in Qatar
Muneera Al-Muhannadi, Khalid Al-Karbi, Hashed Ahmed Ali Amran, Amr Faisal Alsharafi, Omar Taha Alabbas, Khalid Al-Marri, Mohamed Salem
[pdf]
[Abstract]
DOI: 10.5742/MEWFM.2021.94094

Efficacy of curcumin on inflammatory pain across different disorders: a systematic review and meta-analysis of Randomized controlled trials
Khalid Al-Karbi, Muneera Al-Muhannadi, Yosaf Al-Rabeei, Rashed J. Al-Kubaisi, Ahamad Bawazir, Mohamed H Mahmoud
[pdf]
[Abstract]
DOI: 10.5742/MEWFM.2021.94095

Teachers' awareness regarding first-aid management and control of epistaxis inside schools in Taif region, Saudi Arabia
Sattam Aljuaid, Rahaf A. Alqahtani, Sarah H. Alqasem, Yara T. Alsulaimani, Shahad A. Alqahtani, Shmookh M. Alsalmi, Rawan M. Altowairqi
[pdf]
[Abstract]
DOI: 10.5742/MEWFM.2021.94096

Relationship between Socioeconomic Status and Parental Feeding Practices for Children 3-5 years old
Eman Elsayed Sedik Ibrahim, Rasha Saad Alkholy, Heba Galal Elnahas, Marwa Sayed Mohamed Said
[pdf]
[Abstract]
DOI: 10.5742/MEWFM.2021.94097

Perception, feedback regarding post-surgical complications of tracheostomy
Ali Maeed Suliman Al-Shehri, Alaa Abdulrahman H Alshehri, Wajd Abdulwahab Saeed Almathami, Zoha Saleh A Alghamdi, Afnan Sultan M Alshehri, Azza Mofareh Obaid Almarir, Raghad Abdullah Y Asiri, Rehab Saleh M Al doban, Shuruq Zafer A Alshehri
[pdf]
[Abstract]
DOI: 10.5742/MEWFM.2021.94098

Assessment of Health Care Workers' Knowledge and Practice Toward Infection Standard Precautions in Primary Health Care setting, Buraidah, Saudi Arabia
Hanein Saad ALjohani, Amel Abdalrahim Sulaiman
[pdf]
[Abstract]
DOI: 10.5742/MEWFM.2021.94098

Population and Community Studies

Special Editorial: Bashing and murder of doctors and health care workers in Myanmar
Lesley Pocock
[pdf]
[Abstract]
DOI: 10.5742/MEWFM.2021.94099

Prevalence, Awareness and Perception of Influenza Vaccine among Geriatrics in Abha region, Saudi Arabia
Mona Majrashi, Abdulrahman Majrashi, Amani Osman, Safar Abadi Al-Saleem
[pdf]
[Abstract]
DOI: 10.5742/MEWFM.2021.94099

The pattern of diabetic foot and its complications in Albaha, Saudi Arabia
Ahmed H AlGhamdi, Ali G AlGhamdi, Anwar A AlGhamdi, Mohammed A Aldokhi, Amal M AlZahrani, Ebtehal S AlGhamdi, Ahmed A AlZahrani, Riyadh Abdullah Alghamdi
[pdf]
[Abstract]
DOI: 10.5742/MEWFM.2021.94099

Awareness regarding diabetic peripheral neuropathy and its risk factors among diabetics in Muhayil City, Saudi Arabia
Mosa Bahhary, Yahia M. Alkhaldi, Safar A Alsaleem
[pdf]
[Abstract]
DOI: 10.5742/MEWFM.2021.94100

Prevalence, determinants and impact of migraine on quality of life of healthcare workers at primary healthcare centers in Abha City, Saudi Arabia
Fahad Jaber Salman Alfaifi, Mohammed Yahia Qasim, Adel Mushref Al-Harban, Saeed Saad A Alqahtani, Nasser Mubarak S Alshahrani
[pdf]
[Abstract]
DOI: 10.5742/MEWFM.2021.94101

Burnout among the Directors of the Internal Medicine Residency Training Program in Saudi Arabia
Mohammed Abdulrahman Basheikh
[pdf]
[Abstract]
DOI: 10.5742/MEWFM.2021.94102

Review

Barriers to Premarital Thalassemia Screening in Asia
Nazish Jaffar, Laaraib Khan, Urooba Imran Ahmed, Nimra Hussain Vistro, Amna khan, M. Yousuf Memon
[pdf]
[Abstract]
DOI: 10.5742/MEWFM.2021.94101

Middle East Quality Improvement Program
(MEQUIP QI&CPD)


Chief Editor -
Abdulrazak Abyad MD, MPH, MBA, AGSF, AFCHSE

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Publisher -
Lesley Pocock
medi+WORLD International
AUSTRALIA
Email
: lesleypocock@mediworld.com.au
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August 2021 - Volume 19, Issue 8

Efficacy of curcumin on inflammatory pain across different disorders: a systematic review and meta-analysis of Randomized controlled trials

(1) Primary Health Care Corporation, Qatar
(2) Family Medicine Training Department, Qatar

Corresponding author:
Dr Khalid Al-Karbi
Primary Health Care Corporation, Qatar
Email: albraiki86@hotmail.com

Received: July 2021; Accepted: July 2021; Published: August 1, 2021. Citation: Khalid Al-Karbi et al. Efficacy of curcumin on inflammatory pain across different disorders: a systematic review and meta-analysis of Randomized controlled trials. World Family Medicine. 2021; 19(8): 47-55 DOI: 10.5742/MEWFM.2021.94095

Abstract


Aim:
to evaluate randomized controlled trials and perform a meta-analysis to assess the efficacy of curcumin on inflammatory pain in different disorders, in comparison to placebo and traditional pain treatments (NSAIDs and glucosamine plus chondroitin).

Method and design: meta-analysis of randomized controlled trials (RCT).

Data sources: Pubmed and Cochrane library were searched for relevant RCTs from January 1999 to July 2021. Reference lists were manually checked.

Selection criteria: published RCTs comparing curcumin to placebo or other treatment modalities in adults with different pain disorders were eligible for inclusion.

Data collection and criteria: the studies were selected, and their quality was assessed by two review authors. Standardized mean difference (SMD) was used to analyze the continuous outcome using a random effect model.

Results: In all the 15 studies included 1475 subjects. Curcumin was found to be superior in controlling pain against placebo. Moreover, curcumin demonstrated a superior effect in controlling osteoarthritic pain when compared to Glucosamine and Chondroitin combination. However, Curcumin was found to be similarly effective to NSAIDs in controlling pain.
Conclusions: Curcumin was found superior in pain relief against placebo and combination of glucosamine and chondroitin. In addition, it demonstrated equal efficacy in relieving osteoarthritic pain, when compared to NSAIDs.

Key words: curcumin, inflammatory pain, osteoarthritis, NSAIDs, VAS, MOMAC,
meta-analysis, Dysmenorrhea, post-surgical pain.







 


 

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