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Abstract
Background: Saudi
Arabia has the 3rd highest rate of type
one diabetes in the world.
Objectives:
To compare HbA1c, lipid profile and acute
complications in Continuous Subcutaneous
Insulin Infusion (CSII) with multiple
daily injections (MDI) users for type
one diabetes (T1DM) in Taif city, Saudi
Arabia.
Settings and
Design: Sampling was done for all
patients with T1DM and managed either
by MDI or CSII.
Methods:
We recruited all results from May 2015
to January 2018 comparing HbA1c, lipid
profile and acute complications. Data
collection was done through electronic
files. Data was analysed by the Statistical
Package of Social Sciences (SPSS). The
independent sample ‘t‘ test
was used to compare continuous variables.
Chi-square test was used to compare categorical
variables.
Results: Of
214 patients, 137 on MDI and 77 on pump
were recruited. All HbA1c readings were
significantly higher in MDI users (p<0.05).
Acute complications were higher in pump
users (7.8% and 18.2%) compared to MDI
users (2.9% and 6.6%) for each hypoglycaemia
and DKA respectively. The occurrence of
hypoglycaemia and DKA in MDI and pump
users were found to be statistically insignificant,
(p=0.155 and p=0.134) and (p=0.790 and
p=0.721) respectively.
Conclusions:
In patients with T1DM, HbA1c was significantly
higher in MDI users, conversely, DKA was
significantly higher in pump users. Hypoglycemia
showed a significant relation to age in
MDI group. Lipid profile was statistically
insignificant.
Key words:
Comparison, haemoglobin, insulin, pump,
injections, diabetes
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