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March 2022 -
Volume 20, Issue 3


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From the Editor

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Prevalence of depression and anxiety among patients with breast cancer: a cross-sectional study
[Abstract]
[pdf]
Abbas Bukhari, Ali Farsi, Fawaz Albaqami, Abdulaziz Jowharji, Mansoor Radwi, Abdalmohsen Albaqami, Mohammed Fallatah, Abdullah Alammari, Waleed Alghamdi
DOI: 10.5742/MEWFM.2022.952506

Women's Expectations and Satisfaction with the Quality of Antenatal Care at the Primary Health Care Centers in Unaizah City
[Abstract]
[pdf]
Sadeem Alrobiaee, Saulat Jahan
DOI: 10.5742/MEWFM.2022.952507

Pulmonary hypertension and chronic obstructive pulmonary disease in sickle cell diseases
[Abstract]
[pdf]
Mehmet Rami Helvaci, Engin Altintas, Atilla Yalcin, Orhan Ekrem Muftuoglu,
Abdulrazak Abyad, Lesley Pocock
DOI: 10.5742/MEWFM.2022.952508

Positive and negative acute phase reactants in sickle cell diseases
[Abstract]
[pdf]
Mehmet Rami Helvaci, Engin Altintas, Atilla Yalcin, Orhan Ekrem Muftuoglu, Abdulrazak Abyad, Lesley Pocock
DOI: 10.5742/MEWFM.2022.952509

Population and Community Studies

An Overview of Biological Warfare and SARS-CoV-2 as a Potential Biological Agent
[Abstract]
[pdf]
Basem Mohammad Mansour, Deaa Mohammad Alsoleman, Suhail Haydar Alghanem
DOI: 10.5742/MEWFM.2022.9525010

Clinical Audit on Well Baby Services at Primary Health Care Corporation, Qatar
[Abstract]
[pdf]
Noora Alkubaisi, Ansif Pallath Majeed, Hanan Al Mujalli, Abdul Ali Shah,
Sharifullah Khan, Manickavalli M S Anand, Mohammed Asif AbdulGafoor
DOI: 10.5742/MEWFM.2022.9525012

Letter to the Editor

MENA Stem Cells Forum

News Alert

Fake Covid vaccine found in Iran - and beyond?
[Abstract]
[pdf]
Lesley Pocock
DOI: 10.5742/MEWFM.2022.9525016

Review


Cystic Fibrosis: A Review Article
[Abstract]
[pdf]
Hani Raka Karrar, Mahmoud Ismail Nouh, Abdulmohsen Aqeel G. Alanazi,
Sultan Essa Alharbi, Fahad Nuwayfi Almutairi, Hussain Ali Abdullah Alhammad,
Abdullah Ali Hassan Sadeeg, Mohammed Aljunaid Alamin Alsheikh,
Wafa mohammed alshaikh, Mohammed yousef Alyahya, Wejdan Ali Sulieman makki, Hashima Mohammed Alhazmi,
Amal saleem Almutairi, Rehab Salah Aldin Alhendi
DOI: 10.5742/MEWFM.2022.9525014

Case Report

Early-onset CTCL, localized and unilateral - case review

[Abstract]
[pdf]
Ebtisam Elghblawi
DOI: 10.5742/MEWFM.2022.9525015

Original Clinical Research

Study the clinical futures of vitiligo among Yemeni patients in Aden
[Abstract]
[pdf]
Asia Hassan Abdulla Saleh, Amer Bin Al-Zou
DOI: 10.5742/MEWFM.2022.9525017

Surgical treatment and Survival of Gallbladder Cancer Patients: A Systematic Review
[Abstract]
[pdf]
Ali Ibrahim A. Alshehri
DOI: 10.5742/MEWFM.2022.9525019

Shared Decision-Making and its Impact on Medication Adherence among Hypertensive Patients in Northern Saudi Arabia
[Abstract]
[pdf]
Mutasim Almuayqil, Abdusalam Alghamdi, Fahad Alruwaili, Nashmi Al-Etesh
DOI: 10.5742/MEWFM.2022.9525020

Middle East Quality Improvement Program
(MEQUIP QI&CPD)


Chief Editor -
Abdulrazak Abyad MD, MPH, MBA, AGSF, AFCHSE

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Publisher -
Lesley Pocock
medi+WORLD International
AUSTRALIA
Email
: lesleypocock@mediworld.com.au
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March 2022 - Volume 20, Issue 3

Cystic Fibrosis: A Review Article

(1) Pharmaceutical Care Department, General Network for Healthcare Providers Hospital, Jeddah, Makkah, Saudi Arabia.
(2) College of Medicine, Ibn Sina College, Jeddah, Makkah, Saudi Arabia.
(3) King Fahad Medical City, Saudi Arabia.
(4) Unaizah College of Medicine, Saudi Arabia.
(5) Al-Dawaa Pharmacy, Saudi Arabia.
(6) Diaverum Renal Center, Saudi Arabia.
(7) Jazan University, Saudi Arabia.
(8) Ministry of Health, Saudi Arabia.
(9) King Faisal University, Ahsa, Saudi Arabia.
(10) King Abdulaziz Hospital, Saudi Arabia
(11) Security Forces Hospital, Saudi Arabia
(12) Ministry of Health, Makkah, Saudi Arabia

Corresponding author:
Hani Raka Karrar
Pharmaceutical Care Department, General Network for Healthcare Providers Hospital, Jeddah, Makkah, Saudi Arabia.
Tel.: +966 59 060 0263.
Email: hanywell2006m@hotmail.com

Received: January 2022; Accepted: February 2022; Published: March 1, 2022. Citation: Hani Raka Karrar et al. Cystic Fibrosis: A Review Article. World Family Medicine. 2022; 20(3): 58-63. DOI: 10.5742/MEWFM.2022.9525014

Abstract

Cystic Fibrosis is considered one of the most common autosomal recessive diseases that is associated with a decrease in the length of age in a Caucasian population. Also, it is considered as one of the most common life-shortening diseases in the white population in the United States. Cystic fibrosis affects around 30,000 people in the United States and more than 80,000 people worldwide. The incidence rate of this disease is 1 out of 3,500 births per year in the white population in the United States, while the incidence rate of the person becoming a carrier is 1:25 in the Caucasian population, the incidence of the disease is 1:2,500. The main cause for this disease is the mutation in Fibrosis Transmembrane Conductance Regulator (CFTR) gene. This disease is considered a life-threatening genetic disease that causes a buildup of thick, viscous mucus secretions in organ systems. Cystic Fibrosis is considered a multiple system disease, but in most cases, the disease gets worse and mortality increases because of respiratory manifestations such as bronchiectasis. Also, pancreatic damage in children is followed by severe wasting, malabsorption, and mortality is one of the recorded observations in children. This article aims to provide a brief introduction and the clinical picture of the disease, Etiology, Pathophysiology, Epidemiology, Nutrition, Prevention, and good practice management advice.

Keywords: Cystic Fibrosis, Bronchiectasis, Review Article, Airway Clearance Therapy,
Fibrosis Transmembrane Conductance Regulator gene.







 


 

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