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Current Issue
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December2022 -
Volume 20, Issue 12


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From the Editor

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Knowledge and phobias about the use of topical corticosteroids among the Saudi population: A cross-sectional study
[Abstract]
[pdf]
Manar A. Alotaibi, Haifa A. Alotaibi, Khalid A. Bin Abdulrahman
DOI: 10.5742/MEWFM.2022.95251401

Awareness of Nutritional Screening and Support Among surgeons
[Abstract]
[pdf]
Wesam M. Alsahafi, Ahmed F. Alajrafi, Assim A. Felemban,
Mohannad S. Hantoush, Abdulelah K. Bahabri, Abdullah A. Almohammadi
DOI: 10.5742/MEWFM.2022.95251402

Emotional Intelligence and Burnout among Medical Students at a Public Saudi University
[Abstract]
[pdf]
Khalid A. Bin Abdulrahman, Noura T. AlRowaitea, Lina Z. Alshalan,
Rawan A. Bayamin, Yara A. Alfraih, May S. Alharbi
DOI: 10.5742/MEWFM.2022.95251403

Perspective of Evidence-Based Medicine among Egyptian Family Physicians in Egypt
[Abstract]
[pdf]
Hala Hussein, Mohamed Aladdin, Aly Shalaby
DOI: 10.5742/MEWFM.2022.95251404

Type III Supracondylar humeral fracture in children treated by 3 lateral versus 2 cross K-wire fixation, Aden, Yemen
[Abstract]
[pdf]
Abdulsalam Abdullah Hadi Mohsen, Nazih Ali Abdulrahman Omer,
Mustafa Kamal Mustafa
DOI: 10.5742/MEWFM.2022.95251405

Does the number of hours spent daily on social media have any correlation to the Irritable Bowel Syndrome Symptoms in Saudi Adults?
[Abstract]
[pdf]
Fahad A Alateeq, Waleed M Alhuzaim, Hamad N Alhamlan, Abdalaziz B Alyousef, Abdullah H Alorainy, Abdulmalik E Aldhafyan, Ahmed A Basendwah, Turki Y Alassaf
DOI: 10.5742/MEWFM.2022.95251406

Regional COVID

The Impact of the COVID-19 Pandemic on Makkah City's Health Programs Performance
[Abstract]
[pdf]
Ahmad Alturkstani, Raghad Alhajaji, Sari Ibrahim Asiri, Mayada Albarakati, Malaz Elbashir Ahmed, Mayada Samkari, Rami Al Amri, Samar Jalal,
Amal Habhab, Mohammed Almahmudi
DOI: 10.5742/MEWFM.2022.95251407

Depression, Anxiety and Stress among health care workers during the COVID-19 pandemic in Jazan city, Kingdom of Saudi Arabia
[Abstract]
[pdf]
Amal Jaber Alfaifi, Ahmed Yahia Abdaly, Sultan Musa Alallah, Maged El-Setouhy
DOI: 10.5742/MEWFM.2022.95251408

Population and Community Studies

Awareness of cardiovascular diseases and their associated risk factors among the general population in Hail city, Saudi Arabia
[Abstract]
[pdf]
Kareemah Salem Alshurtan, Alazmmy Abdullaziz Hamed H, Abdulrahman Saleh Hussain Alasiri, Mohammed Rubayyi Alruwaytie,
Alshammari Hamad Ali H, Salman Sayah Alonazi, Alanazi Abdullah Aziz S,
Mohammad Ayedh Ali Alswaidan, Alamri Rayan Mohammed B,
Altarjami Mohammed Hamed S
DOI: 10.5742/MEWFM.2022.95251411

Prevalence and Awareness of Varicose Veins (VV) among Teachers and the General Population of Taif City, Saudi Arabia
[Abstract]
[pdf]
Nawaf K. Althobaiti, Bashir A. Amin, Sultan M. Alzahrani, Abdulrahman D. Alhamyani, Abdulrahman M. Alamri, Khalid M. Alzahrani
DOI: 10.5742/MEWFM.2022.95251414

Awareness of cast complications among fracture patients in Aseer region, Saudi Arabia
[Abstract]
[pdf]
Turki Ahmed Alqahtani, Sultan Mohammed Abdullah Alkorbi,
Abdulrahman Nasser Alqahtani, Bandar Mohammed Mushabbab Asiri,
Abdulaziz Saad Mohammed Alshahrani, Hassan Adel Hassan Alasiri,
Abdulelah Gasem Yahya Alfaifi
DOI: 10.5742/MEWFM.2022.95251416

Review

Progesterone Aids in Alleviation of Nicotine Withdrawal Symptoms: A Systematic Review
[Abstract]
[pdf]
Hijab Zafar, Maria Binte Sarfraz, Muhammad Mazhar, Saman Fatima,
Muhammad Zain ul Hasan, Arsalan Rasheed, Wasif Safdar, Humna Khali,
Madiha Arif
DOI: 10.5742/MEWFM.2022.95251476

Can Probiotics be used as an adjuvant thereby for diabetes - hope or hype? Narrative review of the literature
[Abstract]
[pdf]
Mohammed Alfawaz, Wafi Almutawa, Fawaz Abdullah M Alfawaz, Ali M. Almutawa
DOI: 10.5742/MEWFM.2022.95251477

Original Clinical Research

Perspective of caregivers towards early signs of memory decline in their elderly relatives among the Saudi population
[Abstract]
[pdf]
Walid alkeridy, Taim Muayqil, Ahmed Shawky mohammedin, Abdulrahman Mohammed Alhayssoni, Mohammed mubarak alswoaiegh, Abdulrahman Abdullah Altalasi, Rayan Abdulrahman bin Muneef, Saad Ahmed Alhaddab
DOI: 10.5742/MEWFM.2022.95251478

Awareness of Degenerative Cervical Myelopathy Among Medical Students in Aseer region, Saudi Arabia
[Abstract]
[pdf]
Shehata Farag Shehata, Saeed Ali Alqarni, Saud Muhammed ayyashi, Mohammed Saeed ALmsodi, Bader Saad Alshahrani, Salem Hassan Alshehri, Saeed Mofareh Alshehri, Mohammed Hassan Alshehri
DOI: 10.5742/MEWFM.2022.95251480

Impact of prolonged use of facemask in COVID-19 pandemic on the health of the population of Jeddah, Saudi Arabia
[Abstract]
[pdf]
Fathi El-Gamal, Hanan Alhazmi, Mohammad Jaad, Jayan Algarni, Mohammed Alnemary,
Abdullah Alzahrani
DOI: 10.5742/MEWFM.2022.95251485

Case Report

Acute Hemolytic Anemia Following Semaglutide Injection: A Case Report
[Abstract]
[pdf]
Abdullah Khlofh Saleh, Majed Mohammed Al Saleh, Osama Abdulaziz Albaqar, Hanan Ali Mohmmed Khoziee, Abdullah Hassan Algarni, Adnan Saleh Alghamdi, Nasser Khalil Albaqqar
DOI: 10.5742/MEWFM.2022.95251483

Faculty Development

Family Members Involvement in Patient Care: Are They Invited?
[Abstract]
[pdf]
Yahia A Alghtanie, Abdallah M Alasmari, Saleh H Alomeer, Khalid S Alqahtani, Abdulaziz Gaber Alshehri, Abdulrahman Albukhodaah
DOI: 10.5742/MEWFM.2022.95251484

Middle East Quality Improvement Program
(MEQUIP QI&CPD)


Chief Editor -
Abdulrazak Abyad MD, MPH, MBA, AGSF, AFCHSE

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Publisher -
Lesley Pocock
medi+WORLD International
AUSTRALIA
Email
: lesleypocock@mediworld.com.au
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December 2022 - Volume 20, Issue 12

Acute Hemolytic Anemia Following Semaglutide Injection:
A Case Report

(1) MD, Family Medicine Consultant, Ministry of Health, Abha, Saudi Arabia
(2) MBBS, Family Medicine Resident, Family Medicine Program, Abha, Saudi Arabia
(3) MBBS, King Abdulaziz University Hospital, Jeddah, Saudi Arabia
(4) Medical Student, Albaha University, Saudi Arabia(5) BPH, Ministry of Health, Saudi Arabia

Corresponding Author
Dr. Abdullah Khlofh Saleh
Email: d-khlofh@hotmail.com

Received: October 2022 Accepted: November 2022; Published: December 1, 2022. Citation: Abdullah Khlofh Saleh et al. Acute Hemolytic Anemia Following Semaglutide Injection: A Case Report. World Family Medicine. 2022; 20(12): 139-143 DOI: 10.5742/MEWFM.2022.95251483

Abstract


Background: Drug-induced immune hemolytic anemia is a serious adverse reaction that may result from drug administration, especially in cases of glucose-6-phospate dehydrogenase (G6PD) deficiency.

Objective: To report a case of acute hemolytic anemia in a 30-year-old Saudi male after receiving Semaglutide injection.

Case Report: A 30-year-old Saudi male with G6PD deficiency presented to the Emergency Department of Aseer Central Hospital, Abha City, Saudi Arabia with acute onset of yellow discoloration of the eyes, palpitation, mild backache, fatigue, and dark urine. The symptoms started one day after receiving the second dose of Semaglutide injection. He looked pale and the sclera were slightly icteric. Laboratory investigations showed high serum levels of liver enzymes and the total bilirubin. The RBCs count as well as the hemoglobin and the hematocrit were low, while reticulocyte count was high. The diagnosis was acute hemolytic anemia, most probably triggered by a recent Semaglutide injection. Following the discontinuation of Semaglutide, his clinical condition improved.

Conclusions: G6PD deficiency should be considered in all clinical settings, and the hemolytic conditions that can possibly be precipitated by drugs not well known to cause hemolysis. Screening of newborn infants to early detect G6PD deficiency early is highly recommended, especially in those with positive family history of G6PD.

Key Words: Semaglutide, Hemolytic anemia, G6PD deficiency, Case report.







 


 

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