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November/December 2015 -
Volume 13, Issue 8
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From the Editor

 
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Original Contribution/Clinical Investigation




 

 

 

 

<-- Saudi Arabia -->
Indications and findings of upper gastrointestinal endoscopy (UGIE) in patients of Gizan, Saudi Arabia: A retrospective study
[pdf version]
Hussein Ageely

<-- Turkey -->
Chronic obstructive pulmonary disease may be one of the terminal endpoints of the sickle cell diseases
[pdf version]
Mehmet Rami Helvaci, Sibel Dogru

<-- Saudi Arabia -->
Enabling Factors and Barriers among Health Policy Makers toward Utilization of National Medical Research’ Recommendations in Jeddah, 2010
[pdf version]
Mahmoud Abdullah Al-Zahrani, Rajaa Al- Raddadi, Adel Ibrahem

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International Health Affairs



<-- Pakistan -->
Strategies for the Prevention of Hepatitis B, Hepatitis C and Human Immunodeficiency Virus infection in the Paediatric Population of Developing Countries
[pdf version]

Sina Aziz, Waris Qidwai

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Evidence Based Medicine



<-- Saudi Arabia -->
Critical Reading of an Article about Therapy
[pdf version]
Mazen Ferwana, Ahmed Al Saileek

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Chief Editor -
Abdulrazak Abyad MD, MPH, MBA, AGSF, AFCHSE

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Lesley Pocock
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November/December 2015 - Volume 13 Issue 8

From the Editor
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Chief Editor:
A. Abyad
MD, MPH, AGSF, AFCHSE
Email: aabyad@cyberia.net.lb

In this issue of the journal the third paper on evidence based medicine is presented. The paper is about Critical Reading of an Article about Therapy. The main objective of this paper is to understand the process of assessing the quality of a therapy article and how to apply its results to clinical practice. Specifically, the learners are expected to be able to: Assess the validity of a therapy paper; Determine the importance of the results of a valid therapy paper; and Determine how a valid and important evidence from therapy paper be applied to patient care.

A retrospective study was carried out at KFCH over an 11-years period from 1994 to 2005. All patients (3287), age of 12 years and above referred for endoscopy unit were enrolled in this study. The objectives of this study were to identify the common indications and findings of upper gastrointestinal (GI) endoscopy in patients presenting to King Fahd Central Hospital (KFCH) in Gizan town Southwest Saudi Arabia, and to furthermore, determine the associations between and the common endoscopic findings and some selected clinical and demographic variables. A total of 3287 patients were included in the study with a mean age of 45.3 years (SD ± 18.4), Indications for upper GI endoscopy included upper gastrointestinal (GI) bleeding (23.3%), with a significant difference between males and females (p-value = 0.000), Epigastric pain (15.7%), Acid Peptic Disease (APD) (14.4%), Dyspepsia (7.5%) and regular follow-up (6.5%). The results of the study suggested that UGI bleeding was the main indication for UGI E in the vast majority of our patients. In addition to that three common diseases; Oesophageal Varices, Gastritis and Oesophagitis were the main findings of the UGI E among study population. Preventive measures should be adopted to cope with the situation and to prevent complications of esophageal and gastritis diseases among Gizan population.

A paper from Pakistan looked at the Strategies for the Prevention of Hepatitis B, Hepatitis C and Human Immunodeficiency Virus infection in the Paediatric Population of Developing Countries. After a brief background about the epidemiology of Hepatitis B, C and HIV, strategies for their prevention are discussed in the paediatric population of developing countries. These strategies are focused on mother to child transmission, misuse of injections, use of infected needles, myths and use of material infected with the hepatitis positive patient such as a comb, tooth brush etc. Malnutrition and its relationship with Tuberculosis and HIV infection are discussed. World Health Organization (WHO) guidelines on the management of malnutrition, Tuberculosis and HIV are discussed briefly. A real scenario highlighting the existence of HBV, HCV and HIV is described. Finally role of policy makers, NGO, WHO and local governments in the prevention of HBV, HCV and HIV in the paediatric population is discussed.

A cross sectional descriptive study was conducted in MOH hospitals and PHCC sectors and private hospitals and dispensaries in Jeddah. Self administered questionnaires were distributed to 210 general managers and medical directors of MOH governmental and private hospitals plus MOH PHCC supervisors and only medical directors of private dispensaries. Data were collected by 3 trained data collectors. It was entered and analyzed using SPSS version 16. Ethical considerations were ensured. The current study aim at identifying enabling factors and determine barriers among health policy makers toward utilization of national medical research' recommendations in Jeddah city, Saudi Arabia, 2010.

There is concern for the international community that research findings are not being utilized in the implementation of research future wise. 19% of the respondents addressed that they received recommendation from the previously conducted research while only 12.4% indicated that there was previous research conducted in their institution.

The authors concluded that among the interviewed health policy-makers there was a gap between the perceived importance of the research from one side and its conduction and utilization of its recommendations on the other side. The reported barriers were mainly remediable as being attributed chiefly to modifiable subjective factors driven from the lack of knowledge and experience about research methodology. In addition, the insufficient time perceived as a barrier reflects the vision of the studied institute which were not focusing in part of it on conduction of research and incorporating it in its plan and regular routine work.

A paper from Turkey looked at Chronic obstructive pulmonary disease as one of the terminal endpoints of the sickle cell diseases. All patients with the SCDs were taken into the study. The study included 411 patients with the SCDs (199 females and 212 males). There were 60 patients (14.5%) with the COPD. Mean age of the patients was significantly higher in the COPD group (33.0 versus 29.5 years, P=0.005). The male ratio was significantly higher in the COPD group, too (80.0% versus 46.7%, P<0.001). Smoking was also higher in the COPD group, significantly (36.6% versus 9.9%, P<0.001). Parallel to the smoking, alcoholism was also higher among the COPD cases, significantly (3.3% versus 0.8%, P<0.05). The authors concluded that SCDs are chronic catastrophic processes on vascular endothelium particularly at the capillary level, and terminate with accelerated atherosclerosis induced end-organ failures in early years of life. COPD may be one of the terminal endpoints of the diseases.



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