JOURNAL
Current Issue
Journal Archive
.............................................................
September 2020 -
Volume 18, Issue 9

View this issue in pdf format
........................................................
From the Editor

Editorial
A. Abyad (Chief Editor)
........................................................

 

Original Contribution

Prevalence of Diabetes Distress among People with Type 2 Diabetes at Primary Health Care in Qatar: A cross-sectional Study
[Abstract]
[pdf]
Hani Abdalla, Ahmed Alnuaimi,Alawiya Gadallah, Hagir Salih, Kamar Badei , Mohammed Mushtaha, Ben Illigens
DOI: 10.5742MEWFM.2020.93850

Risk factors and complications of cataract disease in type two diabetic patients in Taif city
[Abstract]
[pdf]
Amal Saleh Alfaqeeh , Ayman Abdelbaky Atalla, Fatima Moeesh Altalhi, Futoon Abdullah Aljouid, Ohoud Owayedh Almutairi, Rawan Yasseen Bamjboor, Ameerah Saleh Bajaber
DOI: 10.5742MEWFM.2020.93851

Self-Medication with Antibiotics among Medical Students in Karachi: A Cross-Sectional Institution Based Study
[Abstract]
[pdf]
Hunain Asif, Tafazzul Hyder Zaidi, Kiran Mehtab, Marina Aziz, Khadija Khalid,
Maham Shamim Shaikh, Mahnoor, Sidra Zai, Batool Zehra, Maryam Nadeem,
Mirza Muhammad Hashim, Ramal Fatima, Syed Muhammad Abbas, Warda Batool
DOI: 10.5742MEWFM.2020.93866

Prevalence and risk factors of nonalcoholic fatty liver disease in primary health care centers among subjects examined by abdominal ultrasound in Qatar: A case-control study
[Abstract]
[pdf]
Abdelwahed Samir A. Abougazia , Ahmed Sameer Alnuaimi , Amal Said Mahran , Tamer Fathi Ali , Ahmed Abdelsattar Khedr , Tawhid Mohamed Mowafy
DOI: 10.5742MEWFM.2020.93852

Fibromyalgia in patients with psoriasis
[Abstract]
[pdf]
Abdulsatar J. Mathkhor. Jinan Q. Mohammed. Abdulnasser H. Abdullah. Amer S. Khudhairy. Hassanain H. Nasrullah
DOI: 10.5742MEWFM.2020.93853

Covid 19 in the Region or Covid Related Issues

Family Medicine Residents Mentoring During Covid-19 Pandemic and Beyond
[Abstract]
[pdf]
Muna Aseel, Fawziya Al Hor, Khalid Al-Karbi, Ahmad Bawazir, Muneera Al-Muhannadi, Isameldin Abdelbagi, Mohamed H. Mahmoud
DOI: 10.5742MEWFM.2020.93854

Trust and psychological safety in a virtual healthcare team
[Abstract]
[pdf]
Sanjeewa Sumathipala
DOI: 10.5742MEWFM.2020.93855

Implications of COVID -19 pandemic on Family medicine Residency training program and ACGME requirements at Qatar
[Abstract]
[pdf]
Rasha Moussa, Fawziya Al Hor, Muna Aseel.
DOI: 10.5742MEWFM.2020.93856

Population and Community Studies

Role of Family Doctors and Primary Health Care in COVID-19 Pandemic
[Abstract]
[pdf]
Faisal Abdullatif Alnaser
DOI: 10.5742MEWFM.2020.93857

Perceptions of millennials of twenty first century regarding position of women in Pakistani society
[Abstract]
[pdf]
Hana Javed , Tafazzul Hyder Zaidi , Kiran Mehtab
DOI: 10.5742MEWFM.2020.93858

What a high prevalence of rheumatic heart disease in sickle cell patients
[Abstract]
[pdf]
Mehmet Rami Helvaci, Ramazan Davran, Abdulrazak Abyad, Lesley Pocock
DOI: 10.5742MEWFM.2020.93859

Clinical Characteristics and Treatment of Cryptorchidism in Adults: Our Experience in Alsaidi hospital, in Aden, Yemen
[Abstract]
[pdf]
Ali Ahmed Salem Hatroom
DOI: 10.5742MEWFM.2020.93860

Glucose- 6-phosphate dehydrogenase deficiency: A review
[Abstract]
[pdf]
Sanjeewa Sumathipala
DOI: 10.5742MEWFM.2020.93862

Review

Thyroid disease in pregnancy and screening
[Abstract]
[pdf]
Shahzad Ahmed, Kashif Ali Raza
DOI: 10.5742MEWFM.2020.93861

Irritable bowel syndrome: Clinical review
[Abstract]
[pdf]
Kashif Ali Raza, Shahzad Ahmed
DOI: 10.5742MEWFM.2020.93863

Early effects of smoking and environmental pollution on lung function, respiratory symptoms and allergic disorders
[Abstract]
[pdf]
Fathi M. El-Gamal, , Ahmed M. Alserihi, Abdullah O. Alhasawi, Abdulrahman S. Alshamrani, Eyad M. Alghamdi, Hussain S. Althumali, Mohammed A. Al-Ghamdi
DOI: 10.5742MEWFM.2020.93867

Case Report

Alopecia Syphilitica: a case report involving hair loss on scalp and eyebrow
[Abstract]
[pdf]
Muhammad Naeem Barg, Waad Ibrahim Kadori
DOI: 10.5742MEWFM.2020.93864

H Syndrome: A Case Report
[Abstract]
[pdf]
Fadi Farhan Ayyash, Abdalrazzaq Ahmmad Alyassen, Alia Mousa Alkhlaifat, Nasser Eyadeh Banikhaled, Zaid Mousa Ali
DOI: 10.5742MEWFM.2020.93866


Middle East Quality Improvement Program
(MEQUIP QI&CPD)

Chief Editor -
Abdulrazak Abyad MD, MPH, MBA, AGSF, AFCHSE
.........................................................

Editorial Office -
Abyad Medical Center & Middle East Longevity Institute
Azmi Street, Abdo Center,
PO BOX 618
Tripoli, Lebanon
Phone: (961) 6-443684
Fax:     (961) 6-443685
Email: aabyad@cyberia.net.lb
.........................................................

Publisher -
Lesley Pocock
medi+WORLD International
AUSTRALIA
Email: lesleypocock@mediworld.com.au
.........................................................

Editorial Enquiries -
abyad@cyberia.net.lb
.........................................................

Advertising Enquiries -
lesleypocock@mediworld.com.au
.........................................................

While all efforts have been made to ensure the accuracy of the information in this journal, opinions expressed are those of the authors and do not necessarily reflect the views of The Publishers, Editor or the Editorial Board. The publishers, Editor and Editorial Board cannot be held responsible for errors or any consequences arising from the use of information contained in this journal; or the views and opinions expressed. Publication of any advertisements does not constitute any endorsement by the Publishers and Editors of the product advertised.

The contents of this journal are copyright. Apart from any fair dealing for purposes of private study, research, criticism or review, as permitted under the Australian Copyright Act, no part of this program may be reproduced without the permission of the publisher.
September 2020 - Volume 18, Issue 9

What a high prevalence of rheumatic heart disease in sickle cell patients

Mehmet Rami Helvaci (1)
Ramazan Davran (2)
Abdulrazak Abyad (3)
Lesley Pocock (4)

(1) Specialist of Internal Medicine, MD
(2) Specialist of Radiology, MD
(3) Middle-East Academy for Medicine of Aging, MD
(4) medi+WORLD International

Corresponding author:
Prof Dr Mehmet Rami Helvaci,
ALANYA, Antalya, Turkey
Phone: 00-90-506-4708759
Email: mramihelvaci@hotmail.com

Received: July 2020; Accepted: August 2020; Published: September 1, 2020. Citation: Helvaci M R.et al. What a high prevalence of rheumatic heart disease in sickle cell patients World Family Medicine. 2020; 18(9): 80-85 DOI: 10.5742/MEWFM.2020.93859

Abstract


Background: We tried to understand whether or not there is a higher prevalence of rheumatic heart disease (RHD) in the sickle cell diseases (SCDs).
Methods: All patients with the SCDs and controls were studied.

Results: The study included 428 patients with the SCDs (208 females) and 2,855 controls (1,620 females). Mean ages of the SCDs patients were similar in males and females (30.6 versus 30.1 years, respectively, p>0.05). Mean ages of the controls were 40.8 versus 41.8 years, respectively (p<0.001 for both). Although the higher mean ages and female predominance (56.7% versus 48.5%, p<0.001) of the control cases, RHD was detected just in 0.3% of them (eight females and one male). Whereas this ratio was 6.5% (13 females and 15 males) in the SCDs (p<0.001). The mean ages of RHD were 48.2 and 32.2 years in the control and SCDs groups, respectively (p=0.012). The female ratios of RHD were 88.8% and 46.4% in the control and SCDs groups, respectively. Mitral valve was involved in 58.8%, aortic valve was involved in 32.3%, and tricuspid valve was involved in 8.8% of cases with the SCDs. Interestingly, the tricuspid valve was never involved alone instead together with mitral valve in all of the cases.

Conclusion: SCDs induce severe and chronic inflammatory processes on vascular endothelium all over the body, and terminate with end-organ insufficiencies in early years of life. Beside that SCDs cause a moderate to severe immunosuppression by several mechanisms that may be the cause of higher prevalence of RHD in them.

Key words: Rheumatic heart disease, sickle cell diseases, chronic endothelial damage,
immunosuppression

 







 


 
.................................................................................................................